Sarcomatoid carcinoma of urinary bladder: Immunohistochemical study of an uncommon case

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Abstract

A case of sarcomatoid carcinoma of the bladder is reported herein. Immunohistochemical staining with human pancytokeratin antibody was negative, while vimentin staining was strongly positive, suggesting a diagnosis of sarcoma of the bladder. Further immunohistochemical analysis revealed positivity for AE1/AE3 cytokeratins, permitting a correct diagnosis of sarcomatoid carcinoma of the bladder. It can be difficult to distinguish between sarcomatoid carcinoma, undifferentiated carcinoma and sarcoma, particularly if the biopsy specimens are of small size. In rare cases, sarcomatoid tumors may express epithelial markers different from those revealed by human pancytokeratin staining. Copyright © 2002 S. Karger AG, Basel.
Lingua originaleEnglish
pagine (da-a)141-144
Numero di pagine4
RivistaUrologia Internationalis
Volume69
Stato di pubblicazionePublished - 2002

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Urinary Bladder
Carcinoma
Staining and Labeling
Sarcoma
Vimentin
Keratins
Biopsy
Antibodies
Neoplasms

All Science Journal Classification (ASJC) codes

  • Urology

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title = "Sarcomatoid carcinoma of urinary bladder: Immunohistochemical study of an uncommon case",
abstract = "A case of sarcomatoid carcinoma of the bladder is reported herein. Immunohistochemical staining with human pancytokeratin antibody was negative, while vimentin staining was strongly positive, suggesting a diagnosis of sarcoma of the bladder. Further immunohistochemical analysis revealed positivity for AE1/AE3 cytokeratins, permitting a correct diagnosis of sarcomatoid carcinoma of the bladder. It can be difficult to distinguish between sarcomatoid carcinoma, undifferentiated carcinoma and sarcoma, particularly if the biopsy specimens are of small size. In rare cases, sarcomatoid tumors may express epithelial markers different from those revealed by human pancytokeratin staining. Copyright {\circledC} 2002 S. Karger AG, Basel.",
author = "Vincenzo Serretta and Federico Aragona and Francesco Cappello and Vincenzo Serretta",
year = "2002",
language = "English",
volume = "69",
pages = "141--144",
journal = "Urologia Internationalis",
issn = "0042-1138",
publisher = "S. Karger AG",

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T1 - Sarcomatoid carcinoma of urinary bladder: Immunohistochemical study of an uncommon case

AU - Serretta, Vincenzo

AU - Aragona, Federico

AU - Cappello, Francesco

AU - Serretta, Vincenzo

PY - 2002

Y1 - 2002

N2 - A case of sarcomatoid carcinoma of the bladder is reported herein. Immunohistochemical staining with human pancytokeratin antibody was negative, while vimentin staining was strongly positive, suggesting a diagnosis of sarcoma of the bladder. Further immunohistochemical analysis revealed positivity for AE1/AE3 cytokeratins, permitting a correct diagnosis of sarcomatoid carcinoma of the bladder. It can be difficult to distinguish between sarcomatoid carcinoma, undifferentiated carcinoma and sarcoma, particularly if the biopsy specimens are of small size. In rare cases, sarcomatoid tumors may express epithelial markers different from those revealed by human pancytokeratin staining. Copyright © 2002 S. Karger AG, Basel.

AB - A case of sarcomatoid carcinoma of the bladder is reported herein. Immunohistochemical staining with human pancytokeratin antibody was negative, while vimentin staining was strongly positive, suggesting a diagnosis of sarcoma of the bladder. Further immunohistochemical analysis revealed positivity for AE1/AE3 cytokeratins, permitting a correct diagnosis of sarcomatoid carcinoma of the bladder. It can be difficult to distinguish between sarcomatoid carcinoma, undifferentiated carcinoma and sarcoma, particularly if the biopsy specimens are of small size. In rare cases, sarcomatoid tumors may express epithelial markers different from those revealed by human pancytokeratin staining. Copyright © 2002 S. Karger AG, Basel.

UR - http://hdl.handle.net/10447/198480

M3 - Article

VL - 69

SP - 141

EP - 144

JO - Urologia Internationalis

JF - Urologia Internationalis

SN - 0042-1138

ER -