rTMS of supplementary motor area modulates therapy-induced dyskinesias in Parkinson disease

Massimiliano Oliveri, Carlo Caltagirone, Giacomo Koch, Centonze, Antonella Peppe, Brusa, Stanzione, Massimiliano Oliveri

Risultato della ricerca: Articlepeer review

108 Citazioni (Scopus)

Abstract

The neural mechanisms and circuitry involved in levodopa-induced dyskinesia are unclear. Using repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) in a group of patients with advanced Parkinson disease, the authors investigated whether modulation of SMA excitability may result in a modification of a dyskinetic state induced by continuous apomorphine infusion. rTMS at 1 Hz was observed to markedly reduce drug-induced dyskinesias, whereas 5-Hz rTMS induced a slight but not significant increase.
Lingua originaleEnglish
pagine (da-a)623-625
RivistaNeurology
Volume65(4)
Stato di pubblicazionePublished - 2005

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

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