TY - JOUR
T1 - Role of computational modeling in thoracic aortic pathology: A review
AU - Pasta, Salvatore
AU - Pilato, Michele
AU - Amaducci, Andrea
AU - Pasta, Salvatore
AU - Follis, Fabrizio
AU - Lee, Jake J.
AU - D'Ancona, Giuseppe
PY - 2014
Y1 - 2014
N2 - Thoracic aortic diseases are life-threatening conditions causing significant mortality and morbidity despite advances in diagnostic and surgical treatments. Computational methods combined with imaging techniques provide quantitative information of disease progression, which may improve clinical treatments and therapeutic strategies for clinical practice. Since hemodynamic and wall mechanics play important roles in the natural history and progression of aortic diseases, we reviewed the potential application of computational modeling of the thoracic aorta. We placed emphasis on the clinical relevance of these techniques for the assessment of aortic dissection, thoracic aortic aneurysm, and aortic coarctation. Current clinical guidelines and treatment are also described. doi: 10.1111/jocs.12413 (J Card Surg 2014;29:653-662)
AB - Thoracic aortic diseases are life-threatening conditions causing significant mortality and morbidity despite advances in diagnostic and surgical treatments. Computational methods combined with imaging techniques provide quantitative information of disease progression, which may improve clinical treatments and therapeutic strategies for clinical practice. Since hemodynamic and wall mechanics play important roles in the natural history and progression of aortic diseases, we reviewed the potential application of computational modeling of the thoracic aorta. We placed emphasis on the clinical relevance of these techniques for the assessment of aortic dissection, thoracic aortic aneurysm, and aortic coarctation. Current clinical guidelines and treatment are also described. doi: 10.1111/jocs.12413 (J Card Surg 2014;29:653-662)
KW - Aneurysm
KW - Dissecting; Aortic Aneurysm; Aortic Coarctation; Aortic Diseases; Biomechanical Phenomena; Diagnostic Imaging; Disease Progression; Hemodynamics; Humans; Practice Guidelines as Topic; Aorta
KW - Thoracic; Patient-Specific Modeling
KW - Aneurysm
KW - Dissecting; Aortic Aneurysm; Aortic Coarctation; Aortic Diseases; Biomechanical Phenomena; Diagnostic Imaging; Disease Progression; Hemodynamics; Humans; Practice Guidelines as Topic; Aorta
KW - Thoracic; Patient-Specific Modeling
UR - http://hdl.handle.net/10447/376200
UR - http://www.blackwellpublishing.com/journal.asp?ref=0886-0440
M3 - Article
VL - 29
SP - 653
EP - 662
JO - Journal of Cardiac Surgery
JF - Journal of Cardiac Surgery
SN - 0886-0440
ER -