Role of acetaldehyde in alcohol addiction: current evidence and future perspectives

Fulvio Plescia, Carla Cannizzaro, Fulvio Plescia, Silvana Cacace, Silvana Cacace

Risultato della ricerca: Article

10 Citazioni (Scopus)

Abstract

The effects of alcohol have been widely studied during the past century, corroborating the idea that this tinychemical compound acts throughout most of ourneurotransmitter systems since it is capable of inducing addictive behaviour. Two of the most serious problems of alcohol addictionare craving and relapse; several studies have demonstrated that relapse is related to the anxious state which occurs during withdrawal, and it has been proved that this behavioural modifications results from an alteration of the dopaminergic and serotonergic systems. An important role in the neurobiology of alcohol addiction is played by acetaldehyde (ACD), ethanol first metabolite.
Lingua originaleEnglish
Numero di pagine5
RivistaMalta Medical Journal
Volume23
Stato di pubblicazionePublished - 2011

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

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