Role and clinical importance of Helicobacter pylori infection in hemodialysis patients

Giorgio Romano, Maurizio Romano, Bianca Maria Cudia, Francesco Paolo Gioe', Maurizio Li Vecchi, Gerlando Cocchiara, Lucio Lo Coco, Valentina Li Vecchi

Risultato della ricerca: Articlepeer review

7 Citazioni (Scopus)


Dyspepsia is an extrarenal symptom frequently found in hemodialysed patients; it is due to chronic renal failure, and uremic gastritis is a specific associated condition in chronic renal failure (CRF). On the other hand, in the general population, Helicobacter pylori infection is an important dyspepsia-related risk factor; its close connections with gastro-duodenal pathology are already known, above all the peptic disease in a really exclusive way. By observation of a dyalitic group of patients, opportunely matched with a no CRF group, we evaluated CRF-associated uremia and Helicobacter pylori infection which could eventually interact causing symptoms and lesions. A statistical analysis of obtained data allowed us to conclude that, although there is not, from an epidemiological view-point, a larger diffusion of Helicobacter pylori among dyalitic patients compared to general population, moreover the infection is uremia-synergic in causing gastro-duodenal symptoms and lesions. These findings, therefore, suggest systematically investigation a possible Helicobacter pylori infection in CRF patients and its relation to gastritis grading, and searching for probable active peptic lesions.
Lingua originaleItalian
pagine (da-a)81-84
Numero di pagine4
Stato di pubblicazionePublished - 2008

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