Risk factors for contrast induced nephropathy: a study among Italian patients.

Salvatore Novo, Giuseppina Novo, Enrico Hoffmann, Egle Corrado, Salvatore Evola, Francesca Bonura, Monica Lunetta, Salvatore Novo, Francesca Macaione, Giuseppe Fonte, Gaspare Milana, Giuseppina Novo, Salvatore Evola, Enrico Hoffmann, Egle Corrado, Francesca Bonura, Francesca Macaione, Gaspare Milana, Monica Lunetta

Risultato della ricerca: Articlepeer review

22 Citazioni (Scopus)


This study aimed to make a profile of patients at highest risk of developing contrast induced nephropathy (CIN) in order to take appropriate prevention measures. 591 patients undergoing coronary procedures were divided into two groups: patients with (CIN-group) and without (no-CIN) an increase in creatinine level equal or more than 25% from baseline values within 24-48 h after the coronary procedure. All patients underwent an accurate anamnesis, objective exam, hematochemical measurements, and diagnostic exams. The results of this study while confirming that, average age (p = 0.01), diabetes mellitus (p < 0.0001), base line renal insufficiency (p = 0.0001), diuretic therapy (p = 0.002), higher contrast doses (p = 0.01), are associated with a higher risk of contrast-induced nephropathy, also demonstrated that both clinical (p = 0.01) and subclinical (p < 0.0001) atherosclerosis, and higher preprocedural high sensitive C-reactive protein levels (hs- CRP) (p = 0.02) are risk factors for CIN.
Lingua originaleEnglish
pagine (da-a)484-492
Numero di pagine9
RivistaIndian Heart Journal
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

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