Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies

Felice Pecoraro, Jason Lee, Velipekka Suominen, Giovanni Torsello, Gaspar Mestres, Theodosios Bisdas, Felice Pecoraro, Konstantinos P. Donas, Frank Veith, Kenneth Tran, Vincent Riambau, Stefano Fazzini, Sven Seifert, Nilo J. Mosquera, Gergana T. Taneva, Fabio Pozzi Mucelli, Sonia Ronchey, Nicola Mangialardi, Paolo Frigatti, Mirko EscheDavid Minion, Roberto Adovasio, Ronald L. Dalman, Daniele Gasparini, Frank J. Criado, Paul Kubilis, Juha Salenius, Edward Y. Woo, Scott M. Damrauer, Salvatore T. Scali

Risultato della ricerca: Article

Abstract

Background: The prevailing evidence calls for using chimney/snorkel endovascular repair (ch-EVAR) with one or two chimney grafts. No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-EVAR treatment for SRAP placing three or more chimney grafts within the PERICLES Registry. Methods: Data from 517 patients suffering complex aortic pathologies treated by ch-EVAR between 2008 and 2014 at 13 European and U.S. centers were retrospectively reviewed and analyzed. Results: Sixty-seven ch-EVAR-treated patients (12.9% of the entire PERICLES cohort) presented SRAP (83.5% elective, 16.5% urgent). The majority of patients (95.5%) received three chimney grafts; four patients received four chimney grafts. The Endurant device was the most commonly used (35.8%) followed by the Zenith abdominal endograft (19.4%). Overall, 204 chimney grafts were placed (56.7% covered self-expandable, 40.3% covered balloon-expandable stents, and 10.4% bare metal balloon-expandable stents). At a median follow-up of 24 months (range, 0.1-67.0 days), 30-day mortality was 6.1% (4 patients), and the overall mortality was 16.4% (11 patients). Overall survival was 87.4% (range, 79.5%-96.0%) at 1 year, 81.8% (range, 72.2%-92.2%) at 2 years and thereafter. Type IA endoleak was noted in nine patients (13.4%) intraoperatively and successfully treated in seven cases (97.1% technical success). Aneurysm sac diameter significantly decreased from 70.5 ± 19.3 mm to 66.9 ± 20.6 mm (P <.001) at last follow-up. Ischemic stroke or transient ischemic attack were noted in two patients (2.9%). Chimney occlusion was detected in six renal arteries (9.5%) and two superior mesenteric arteries (3.2%). No patients required chronic hemodialysis. All occluded superior mesenteric artery grafts were successfully rescued using endovascular approaches. Conclusions: The midterm use of ch-EVAR for the treatment SRAP seems to be safe, highlighting its applicability for the treatment of rupture threatening pathologies and seal zone lengthening as in type IA endoleaks after EVAR. However, the incidence of type IA endoleaks, chimney graft occlusions, and ischemic stroke rates is higher compared with the prevailing single chimney evidence. Longer follow-up with more cases is needed to establish the exact performance of this treatment in SRAP.
Lingua originaleEnglish
pagine (da-a)1521-1527e1
Numero di pagine8
RivistaJournal of Vascular Surgery
Volume71
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

  • Surgery
  • Cardiology and Cardiovascular Medicine

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    Pecoraro, F., Lee, J., Suominen, V., Torsello, G., Mestres, G., Bisdas, T., Pecoraro, F., Donas, K. P., Veith, F., Tran, K., Riambau, V., Fazzini, S., Seifert, S., Mosquera, N. J., Taneva, G. T., Mucelli, F. P., Ronchey, S., Mangialardi, N., Frigatti, P., ... Scali, S. T. (2020). Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies. Journal of Vascular Surgery, 71, 1521-1527e1.