Renin-Angiotensin System Inhibition in Cardiovascular Patients at the Time of COVID19: Much Ado for Nothing? A Statement of Activity from the Directors of the Board and the Scientific Directors of the Italian Society of Hypertension

Giuseppe Mule', Guido Grassi, Leonardo Alberto Sechi, Claudio Borghi, Guido Iaccarino, Guido Iaccarino, Guido Iaccarino, Carmine Savoia, Arrigo F. G. Cicero, Pietro Minuz, Paolo Mulatero, Guido Iaccarino, Maria Lorenza Muiesan, Massimo Salvetti, Massimo Volpe, Claudio Borghi, Claudio Ferri, Giacomo Pucci

Risultato della ricerca: Articlepeer review

19 Citazioni (Scopus)

Abstract

Cardiovascular diseases, in particular hypertension, as well as the cardiovascular treatment with Renin-Angiotensin System inhibitors such as Angiotensin Converting Enzyme (ACE) inhibitors and Angiotensin Receptor Blockers (ARBs), are claimed once again as mechanisms of Severe Acute Respiratory Syndrome (SARS) during the COVID-19 outbreak due to Cov-2 epidemics. In vitro studies are available to support the eventual role of ACE inhibitors and ARBs in both the promotion and antagonism of the disease. The available literature, indeed, presents contrasting results, all concentrated in experimental models. Evidence in humans is lacking that those mechanisms are actually occurring in the present COVID-19 outbreak. Here we present the reasoned statement of the Italian Society of Hypertension to maintain ongoing antihypertensive treatments. Furthermore, the Italian Society of Hypertension presents its own initiative to investigate the issue using an online questionnaire to collect relevant data in human disease.
Lingua originaleEnglish
pagine (da-a)105-108
Numero di pagine4
RivistaHIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION
Volume27
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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