Renal involvement in psychological eating disorders

Giuseppe Mule', Ugo Rotolo, Gioacchino Li Cavoli

Risultato della ricerca: Article

11 Citazioni (Scopus)

Abstract

Psychological eating disorders--anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder--are an increasing public health problem with severe clinical manifestations: hypothermia, hypotension, electrolyte imbalance, endocrine disorders and kidney failure; they are of interest to nephrologists, but pathophysiological mechanisms in determining the renal involvement are still unclear. We describe pathophysiology, histological features and clinical manifestations of the most frequent psychological eating disorders: AN and BN. Regarding AN, we analyze the recent literature, and identify 3 principal pathways towards renal involvement: chronic dehydration-hypokalemia, nephrocalcinosis and chronic rhabdomyolysis. Regarding BN, we describe the correlation between obesity and many proinflammatory cytokines, chemokines, growth factors and adipokines, having potential metabolic and hemodynamic effects on the kidney and an important role in the pathogenesis of obesity-related renal injury, independently of hypertension and diabetes.
Lingua originaleEnglish
pagine (da-a)c8-c14
Numero di pagine7
RivistaNEPHRON CLINICAL PRACTICE
Volume117
Stato di pubblicazionePublished - 2011

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Bulimia Nervosa
Anorexia Nervosa
Psychology
Kidney
Obesity
Binge-Eating Disorder
Nephrocalcinosis
Rhabdomyolysis
Adipokines
Hypokalemia
Hypothermia
Dehydration
Chemokines
Hypotension
Electrolytes
Renal Insufficiency
Intercellular Signaling Peptides and Proteins
Public Health
Hemodynamics
Cytokines

All Science Journal Classification (ASJC) codes

  • Nephrology

Cita questo

Renal involvement in psychological eating disorders. / Mule', Giuseppe; Rotolo, Ugo; Li Cavoli, Gioacchino.

In: NEPHRON CLINICAL PRACTICE, Vol. 117, 2011, pag. c8-c14.

Risultato della ricerca: Article

Mule', G, Rotolo, U & Li Cavoli, G 2011, 'Renal involvement in psychological eating disorders', NEPHRON CLINICAL PRACTICE, vol. 117, pagg. c8-c14.
Mule', Giuseppe ; Rotolo, Ugo ; Li Cavoli, Gioacchino. / Renal involvement in psychological eating disorders. In: NEPHRON CLINICAL PRACTICE. 2011 ; Vol. 117. pagg. c8-c14.
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