Relationships between maximal oxygen uptake and endothelial function in healthy male adults: a preliminary study.

Gregorio Caimi, Silvio Buscemi, Baldassare Canino, Alessandro Mattina, Giovanni Cerasola, Salvatore Verga, Silvio Buscemi, John A. Batsis, Chiara Buscemi, Mariangela Arnone, Vincenzo Calandrino

Risultato della ricerca: Articlepeer review

20 Citazioni (Scopus)


Aerobic capacity, as indicated by maximal oxygen uptake (VO(2) max) has an important role in contrasting the traditional cardiovascular risk factors and preventing cardiovascular morbidity and mortality. It is known that endothelial function, measured as flow-mediated dilation (FMD) of the brachial artery, is strictly linked to atherogenesis and cardiovascular risk. However, the relationship between VO(2) max and FMD has not been fully investigated especially in healthy non-obese subjects. This preliminary study cross-sectionally investigated the relationship between VO(2) max and FMD in 22 non-obese, healthy sedentary male subjects. Dividing the cohort in two subgroups of 11 subjects each according to the median value of VO(2) max, the FMD was significantly lower in the subgroup with lower VO(2) max (mean ± sem: 7.1 ± 0.7 vs. 9.5 ± 0.8 %; P = 0.035). Absolute VO(2) max (mL min(-1)) was significantly and independently correlated with body fat mass (r = -0.50; P = 0.018) and with FMD (r = 0.44; P = 0.039). This preliminary study suggests that maximal oxygen uptake is independently correlated with endothelial function in healthy non-obese adults. These results are also in agreement with the possibility that improving maximal oxygen uptake may have a favorable effect on endothelial function and vice versa.
Lingua originaleEnglish
pagine (da-a)135-141
Numero di pagine7
RivistaActa Diabetologica
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Fingerprint Entra nei temi di ricerca di 'Relationships between maximal oxygen uptake and endothelial function in healthy male adults: a preliminary study.'. Insieme formano una fingerprint unica.

Cita questo