Recyclable Heterogeneous and Low-Loading Homogeneous Chiral Imidazolidinone Catalysts for alpha-Alkylation of Aldehydes

Risultato della ricerca: Articlepeer review

12 Citazioni (Scopus)

Abstract

Two polystyrene-supported and six homogeneous MacMillan imidazolidinone catalysts were prepared and tested for the asymmetric a-alkylation of propanal with benzodithiolylium tetrafluoroborate. The chiral imidazolidinone was linked to polystyrene through the N-3 atom or through the phenyl ring and their catalytic activity was compared with that of their unsupported precursors. This comparison has allowed us to find an unsupported catalyst that displays high catalytic activity down to 5 or 2 mol% at room temperature with a high level of enantioselectivity also when used with hexanal and 3-phenylpropanal. In addition, one of the heterogeneous materials was revealed to be highly recyclable for at least eight cycles with no loss in efficiency working at the same levels of activity and enantioselectivity as the unsupported counterpart.
Lingua originaleEnglish
pagine (da-a)857-862
Numero di pagine6
RivistaChemPlusChem
Volume79
Stato di pubblicazionePublished - 2014

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.1600.1600???

Fingerprint Entra nei temi di ricerca di 'Recyclable Heterogeneous and Low-Loading Homogeneous Chiral Imidazolidinone Catalysts for alpha-Alkylation of Aldehydes'. Insieme formano una fingerprint unica.

Cita questo