Recognition memory and prefrontal cortex: Dissociating recollection and familiarity processes using rTMS.

Patrizia Turriziani, Massimiliano Oliveri, Carlo Caltagirone, Giacomo Koch, Patrizia Turriziani, Giovanni Augusto Carlesimo, Massimiliano Oliveri

Risultato della ricerca: Article

24 Citazioni (Scopus)

Abstract

Recognition memory can be supported by both the assessment of the familiarity of an item and by the recollection of the context in which an item was encountered. The neural substrates of these memory processes are controversial. To address these issues we applied repetitive transcranial magnetic stimulation (rTMS) over the right and left dorsolateral prefrontal cortex (DLPFC) of healthy subjects performing a remember/know task. rTMS disrupted familiarity judgments when applied before encoding of stimuli over both right and left DLPFC. rTMS disrupted recollection when applied before encoding of stimuli over the right DLPFC. These findings suggest that the DLPFC plays a critical role in recognition memory based on familiarity as well as recollection.
Lingua originaleEnglish
pagine (da-a)23-27
Numero di pagine5
RivistaBehavioural Neurology
Volume19
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Neurology
  • Clinical Neurology

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