Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle

Maria Valeria Raimondi, Giuseppe Daidone, Demetrio Raffa, Fabiana Plescia, Gabriella Cancemi, Stella Maria Cascioferro, Benedetta Maggio, Gabriella Cancemi, Fabiana Plescia, Stella Cascioferro, Demetrio Raffa, Giuseppe Daidone, Maria Valeria Raimondi, Benedetta Maggio

Risultato della ricerca: Article

54 Citazioni (Scopus)

Abstract

In this review we report the recent advances in bioactive system containing pyrazole fused with a five membered heterocycle, covering the time span of the last decade. All of them are represented around the common structure of the pyrazole ring fused with another five membered heterocycle containing the nitrogen, sulfur and oxygen atoms in all their possible combinations. The classification we have used is based in terms of the therapeutic area providing, when possible, some general conclusions on the targets and mechanisms of action as well as the structure-activity relationships of the molecules.
Lingua originaleEnglish
pagine (da-a)732-746
Numero di pagine15
RivistaEuropean Journal of Medicinal Chemistry
Volume97
Stato di pubblicazionePublished - 2015

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Structure-Activity Relationship
Sulfur
Nitrogen
Oxygen
Atoms
Molecules
pyrazole
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

Cita questo

Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle. / Raimondi, Maria Valeria; Daidone, Giuseppe; Raffa, Demetrio; Plescia, Fabiana; Cancemi, Gabriella; Cascioferro, Stella Maria; Maggio, Benedetta; Cancemi, Gabriella; Plescia, Fabiana; Cascioferro, Stella; Raffa, Demetrio; Daidone, Giuseppe; Raimondi, Maria Valeria; Maggio, Benedetta.

In: European Journal of Medicinal Chemistry, Vol. 97, 2015, pag. 732-746.

Risultato della ricerca: Article

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AU - Raimondi, Maria Valeria

AU - Daidone, Giuseppe

AU - Raffa, Demetrio

AU - Plescia, Fabiana

AU - Cancemi, Gabriella

AU - Cascioferro, Stella Maria

AU - Maggio, Benedetta

AU - Cancemi, Gabriella

AU - Plescia, Fabiana

AU - Cascioferro, Stella

AU - Raffa, Demetrio

AU - Daidone, Giuseppe

AU - Raimondi, Maria Valeria

AU - Maggio, Benedetta

PY - 2015

Y1 - 2015

N2 - In this review we report the recent advances in bioactive system containing pyrazole fused with a five membered heterocycle, covering the time span of the last decade. All of them are represented around the common structure of the pyrazole ring fused with another five membered heterocycle containing the nitrogen, sulfur and oxygen atoms in all their possible combinations. The classification we have used is based in terms of the therapeutic area providing, when possible, some general conclusions on the targets and mechanisms of action as well as the structure-activity relationships of the molecules.

AB - In this review we report the recent advances in bioactive system containing pyrazole fused with a five membered heterocycle, covering the time span of the last decade. All of them are represented around the common structure of the pyrazole ring fused with another five membered heterocycle containing the nitrogen, sulfur and oxygen atoms in all their possible combinations. The classification we have used is based in terms of the therapeutic area providing, when possible, some general conclusions on the targets and mechanisms of action as well as the structure-activity relationships of the molecules.

UR - http://hdl.handle.net/10447/137272

M3 - Article

VL - 97

SP - 732

EP - 746

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

SN - 0223-5234

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