TY - JOUR
T1 - Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle
AU - Raimondi, Maria Valeria
AU - Cancemi, Gabriella
AU - Maggio, Benedetta
AU - Daidone, Giuseppe
AU - Cascioferro, Stella Maria
AU - Raffa, Demetrio
AU - Plescia, Fabiana
AU - Cancemi, Gabriella
AU - Plescia, Fabiana
AU - Plescia, Fabiana
AU - Plescia, Fabiana
AU - Cascioferro, Stella
AU - Raffa, Demetrio
AU - Daidone, Giuseppe
AU - Raimondi, Maria Valeria
AU - Maggio, Benedetta
PY - 2015
Y1 - 2015
N2 - In this review we report the recent advances in bioactive system containing pyrazole fused with a five membered heterocycle, covering the time span of the last decade. All of them are represented around the common structure of the pyrazole ring fused with another five membered heterocycle containing the nitrogen, sulfur and oxygen atoms in all their possible combinations. The classification we have used is based in terms of the therapeutic area providing, when possible, some general conclusions on the targets and mechanisms of action as well as the structure-activity relationships of the molecules.
AB - In this review we report the recent advances in bioactive system containing pyrazole fused with a five membered heterocycle, covering the time span of the last decade. All of them are represented around the common structure of the pyrazole ring fused with another five membered heterocycle containing the nitrogen, sulfur and oxygen atoms in all their possible combinations. The classification we have used is based in terms of the therapeutic area providing, when possible, some general conclusions on the targets and mechanisms of action as well as the structure-activity relationships of the molecules.
UR - http://hdl.handle.net/10447/137272
M3 - Article
SN - 0223-5234
VL - 97
SP - 732
EP - 746
JO - European Journal of Medicinal Chemistry
JF - European Journal of Medicinal Chemistry
ER -