Real-time PCR for early diagnosis of Rickettsia conorii and promptmanagement in patients with septic shock and multiple organ failure: two case reports

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Abstract

We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.
Lingua originaleEnglish
Numero di pagine2
RivistaINFECTIOUS DISEASES AND TROPICAL MEDICINE
Stato di pubblicazionePublished - 2015

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Rickettsia conorii
Boutonneuse Fever
Rickettsia
Multiple Organ Failure
Critical Care
Septic Shock
Real-Time Polymerase Chain Reaction
Early Diagnosis
Fever
Anti-Bacterial Agents
Polymerase Chain Reaction

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title = "Real-time PCR for early diagnosis of Rickettsia conorii and promptmanagement in patients with septic shock and multiple organ failure: two case reports",
abstract = "We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.",
author = "{Di Carlo}, Paola and Antonino Giarratano and Celestino Bonura and Raineri, {Santi Maurizio} and Anna Giammanco and Francesca Montalto and Marcello Trizzino",
year = "2015",
language = "English",
journal = "INFECTIOUS DISEASES AND TROPICAL MEDICINE",
issn = "2379-4054",

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T1 - Real-time PCR for early diagnosis of Rickettsia conorii and promptmanagement in patients with septic shock and multiple organ failure: two case reports

AU - Di Carlo, Paola

AU - Giarratano, Antonino

AU - Bonura, Celestino

AU - Raineri, Santi Maurizio

AU - Giammanco, Anna

AU - Montalto, Francesca

AU - Trizzino, Marcello

PY - 2015

Y1 - 2015

N2 - We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.

AB - We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.

UR - http://hdl.handle.net/10447/177117

M3 - Article

JO - INFECTIOUS DISEASES AND TROPICAL MEDICINE

JF - INFECTIOUS DISEASES AND TROPICAL MEDICINE

SN - 2379-4054

ER -