TY - JOUR
T1 - Real-time PCR for early diagnosis of Rickettsia conorii and promptmanagement in patients with septic shock and multiple organ failure: two case reports
AU - Bonura, Celestino
AU - Giarratano, Antonino
AU - Di Carlo, Paola
AU - Giammanco, Anna
AU - Raineri, Santi Maurizio
AU - Montalto, Francesca
AU - Trizzino, Marcello
PY - 2015
Y1 - 2015
N2 - We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.
AB - We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.
UR - http://hdl.handle.net/10447/177117
M3 - Article
SN - 2379-4054
JO - INFECTIOUS DISEASES AND TROPICAL MEDICINE
JF - INFECTIOUS DISEASES AND TROPICAL MEDICINE
ER -