Ready, STAT, go: transcription factors on the move.

Valentina Di Liberto, Valentina Di Liberto, Valeria Cavalli

Risultato della ricerca: Article

Abstract

In this issue of The EMBO Journal, Ben-Yaakov et al (2012) explore the contribution of transcription factors (TFs) in directly communicating information about injury between the axon and the nucleus. They show that multiple TFs bind the retrograde molecular motor dynein in injured axons. Focusing on one TF family, the authors reveal that STAT3 is locally translated and activated in injured axons, and then transported retrogradely to the nucleus to promote survival of peripheral sensory neurons.
Lingua originaleEnglish
pagine (da-a)1331-1333
Numero di pagine3
RivistaEMBO Journal
Volume31
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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  • Cita questo

    Di Liberto, V., Di Liberto, V., & Cavalli, V. (2012). Ready, STAT, go: transcription factors on the move. EMBO Journal, 31, 1331-1333.