Abstract
| Lingua originale | English |
|---|---|
| pagine (da-a) | 477-481 |
| Numero di pagine | 5 |
| Rivista | European Journal of Surgical Oncology |
| Volume | 45 |
| Stato di pubblicazione | Published - 2019 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Oncology
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Quality of life following urinary diversion: Orthotopic ileal neobladder versus ileal conduit. A multicentre study among long-term, female bladder cancer survivors. / Simonato, Alchiede; Verze, Paolo; Lonardi, Cristina; Iafrate, Massimo; D'Elia, Carolina; Bassi, Pierfrancesco; Visalli, Francesco; Saleh, Omar; Toffoli, Laura; Porcaro, Antonio; De Marchi, Davide; Cacciamani, Giovanni; Racioppi, Marco; Niero, Mauro; Gacci, Mauro; Cerruto, Maria Angela; Ciciliato, Stefano; Simonato, Alchiede; Imbimbo, Ciro; Serni, Sergio; Mirone, Vincenzo; Talamini, Renato; Siracusano, Salvatore; Artibani, Walter; De Marco, Vincenzo; Verze, Paolo.
In: European Journal of Surgical Oncology, Vol. 45, 2019, pag. 477-481.Risultato della ricerca: Article
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TY - JOUR
T1 - Quality of life following urinary diversion: Orthotopic ileal neobladder versus ileal conduit. A multicentre study among long-term, female bladder cancer survivors
AU - Simonato, Alchiede
AU - Verze, Paolo
AU - Lonardi, Cristina
AU - Iafrate, Massimo
AU - D'Elia, Carolina
AU - Bassi, Pierfrancesco
AU - Visalli, Francesco
AU - Saleh, Omar
AU - Toffoli, Laura
AU - Porcaro, Antonio
AU - De Marchi, Davide
AU - Cacciamani, Giovanni
AU - Racioppi, Marco
AU - Niero, Mauro
AU - Gacci, Mauro
AU - Cerruto, Maria Angela
AU - Ciciliato, Stefano
AU - Simonato, Alchiede
AU - Imbimbo, Ciro
AU - Serni, Sergio
AU - Mirone, Vincenzo
AU - Talamini, Renato
AU - Siracusano, Salvatore
AU - Artibani, Walter
AU - De Marco, Vincenzo
AU - Verze, Paolo
PY - 2019
Y1 - 2019
N2 - Introduction: Women undergoing radical cystectomy (RC) followed by urinary diversion (UD) for bladder cancer experience a substantial reduction in health-related quality of life (HRQOL). At present, studies comparing long-term QOL outcomes for different UD methods, needed to inform evidence-based choices of bladder reconstruction for female patients, are sparse. Our objective was to compare two common UD methods in terms of their HRQOL outcomes in women. Materials and methods: We retrospectively analysed HRQOL in 73 consecutive female bladder cancer patients having undergone orthotopic ileal neobladder (IONB, N = 24) or ileal conduit (IC, N = 49) following RC between 2007 and 2013 in six Italian academic urological centres. Patients had no evidence of tumour recurrence and were actively followed up. Validated Italian versions of the European Organisation for Research and Treatment of Cancer (EORTC) generic (QLQ-C30) and bladder-cancer-specific (QLQ-BLM30) questionnaires were used to evaluate HRQOL. Results: Patients in the IONB group were significantly younger than those in the IC group (median age: 67 and 73 years, respectively, p = 0.02). Barring that, the two groups did not present statistically significant differences in median length of follow-up (43 vs 54 months), pathological stage, grading of the neoplasm, or adjuvant chemo - or radiotherapy. No significant differences in QOL were found between the groups, with the exception of financial difficulties, affecting IONB patients significantly more than IC patients (mean score on a scale of 0–100: 33.3 ± 29.5 vs 18.4 ± 19.3, respectively; p = 0.05). Conclusion: Financial difficulties was the only HRQOL item to differ between the two UD groups.
AB - Introduction: Women undergoing radical cystectomy (RC) followed by urinary diversion (UD) for bladder cancer experience a substantial reduction in health-related quality of life (HRQOL). At present, studies comparing long-term QOL outcomes for different UD methods, needed to inform evidence-based choices of bladder reconstruction for female patients, are sparse. Our objective was to compare two common UD methods in terms of their HRQOL outcomes in women. Materials and methods: We retrospectively analysed HRQOL in 73 consecutive female bladder cancer patients having undergone orthotopic ileal neobladder (IONB, N = 24) or ileal conduit (IC, N = 49) following RC between 2007 and 2013 in six Italian academic urological centres. Patients had no evidence of tumour recurrence and were actively followed up. Validated Italian versions of the European Organisation for Research and Treatment of Cancer (EORTC) generic (QLQ-C30) and bladder-cancer-specific (QLQ-BLM30) questionnaires were used to evaluate HRQOL. Results: Patients in the IONB group were significantly younger than those in the IC group (median age: 67 and 73 years, respectively, p = 0.02). Barring that, the two groups did not present statistically significant differences in median length of follow-up (43 vs 54 months), pathological stage, grading of the neoplasm, or adjuvant chemo - or radiotherapy. No significant differences in QOL were found between the groups, with the exception of financial difficulties, affecting IONB patients significantly more than IC patients (mean score on a scale of 0–100: 33.3 ± 29.5 vs 18.4 ± 19.3, respectively; p = 0.05). Conclusion: Financial difficulties was the only HRQOL item to differ between the two UD groups.
UR - http://hdl.handle.net/10447/352440
M3 - Article
VL - 45
SP - 477
EP - 481
JO - European Journal of Surgical Oncology
JF - European Journal of Surgical Oncology
SN - 0748-7983
ER -