Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement

Arturo Silvestri; Anna Maria Almerico; Antonino Lauria; Giampaolo Barone; Chiara Patella; Ilenia Abbate; Noemi Gambino

Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement

Arturo Silvestri, Anna Maria Almerico, Antonino Lauria, Giampaolo Barone, Chiara Patella, Ilenia Abbate, Noemi Gambino

Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche

Risultato della ricerca: Article › peer review

16 Citazioni (Scopus)

Abstract

Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.

Lingua originale	English
pagine (da-a)	5125-5128
Numero di pagine	4
Rivista	Tetrahedron Letters
Volume	49
Stato di pubblicazione	Published - 2008

All Science Journal Classification (ASJC) codes

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???subjectarea.asjc.3000.3002???
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title = "Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement",

abstract = "Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.",

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journal = "Tetrahedron Letters",

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T1 - Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement

AU - Silvestri, Arturo

AU - Almerico, Anna Maria

AU - Lauria, Antonino

AU - Barone, Giampaolo

AU - Patella, Chiara

AU - Abbate, Ilenia

AU - Gambino, Noemi

PY - 2008

Y1 - 2008

N2 - Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.

AB - Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.

UR - http://hdl.handle.net/10447/43922

M3 - Article

VL - 49

SP - 5125

EP - 5128

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

ER -

Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement

Abstract

All Science Journal Classification (ASJC) codes

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