Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement

Giampaolo Barone, Antonino Lauria, Anna Maria Almerico, Arturo Silvestri, Chiara Patella, Ilenia Abbate, Noemi Gambino

Risultato della ricerca: Article

14 Citazioni (Scopus)

Abstract

Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.
Lingua originaleEnglish
pagine (da-a)5125-5128
Numero di pagine4
RivistaTetrahedron Letters
Volume49
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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