Pulmonary vascular endothelium: The orchestra conductor in respiratory diseases

Maria Rosaria Bonsignore, Alice Huertas, Laurence Dewachter, Christophe Guignabert, Peter Bärtsch, Mark T. Gladwin, Laurent Savale, Marc Humbert, Theodoros Vassilakopoulos, Peter Dorfmüller, Peter Dorfmüller, Theodoros Vassilakopoulos, Tom Kotsimbos, Anh Tuan Dinh-Xuan, Ugo Testa, Martin R. Wilkins, Jahar Bhattacharya, Joan A. Barberà, Sunita Bhattacharya, Olivier Sanchez

Risultato della ricerca: Articlepeer review

36 Citazioni (Scopus)

Abstract

The European Respiratory Society (ERS) Research Seminar entitled “Pulmonary vascular endothelium: orchestra conductor in respiratory diseases - highlights from basic research to therapy” brought together international experts in dysfunctional pulmonary endothelium, from basic science to translational medicine, to discuss several important aspects in acute and chronic lung diseases. This review will briefly sum up the different topics of discussion from this meeting which was held in Paris, France on October 27–28, 2016. It is important to consider that this paper does not address all aspects of endothelial dysfunction but focuses on specific themes such as: 1) the complex role of the pulmonary endothelium in orchestrating the host response in both health and disease (acute lung injury, chronic obstructive pulmonary disease, high-altitude pulmonary oedema and pulmonary hypertension); and 2) the potential value of dysfunctional pulmonary endothelium as a target for innovative therapies.
Lingua originaleEnglish
Numero di pagine13
RivistaEuropean Respiratory Journal
Volume51
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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