Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whethewherecardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as wellas cardiovascular diseases in psoriasis patients. Objective. The objective of this study was to estimate cardiovascular risk score inpsoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUOREproject risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate ofcoronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other thanpsoriasis was performed. CUORE project risk score was higher in patients than controls (6.80 6.34 versus 4.48 4.38, < 0.001).Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was notrelated to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted.
|Numero di pagine||6|
|Rivista||Dermatology Research and Practice|
|Stato di pubblicazione||Published - 2013|
All Science Journal Classification (ASJC) codes