Psoriasis and cardiovascular risk: Assessment by cuore project risk score in Italian patients

Doukaki, S.

Risultato della ricerca: Article

8 Citazioni (Scopus)

Abstract

Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whethewhere cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients. Objective. The objective of this study was to estimate cardiovascular risk score in psoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUORE project risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate of coronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other than psoriasis was performed. CUORE project risk score was higher in patients than controls (6.80 6.34 versus 4.48 4.38, < 0.001). Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was not related to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted.
Lingua originaleEnglish
pagine (da-a)1-6
Numero di pagine6
RivistaDermatology Research and Practice
Volume2013
Stato di pubblicazionePublished - 2013

Fingerprint

Psoriasis
Skin Diseases
Longitudinal Studies
Case-Control Studies
Life Style
Heart Diseases
Outpatients
Cardiovascular Diseases
Population

All Science Journal Classification (ASJC) codes

  • Dermatology

Cita questo

@article{f00664cb8b8842daaa117f427008d87c,
title = "Psoriasis and cardiovascular risk: Assessment by cuore project risk score in Italian patients",
abstract = "Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whethewhere cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients. Objective. The objective of this study was to estimate cardiovascular risk score in psoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUORE project risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate of coronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other than psoriasis was performed. CUORE project risk score was higher in patients than controls (6.80 6.34 versus 4.48 4.38, < 0.001). Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was not related to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted.",
author = "{Doukaki, S.} and Bongiorno, {Maria Rita} and Valentina Caputo",
year = "2013",
language = "English",
volume = "2013",
pages = "1--6",
journal = "Dermatology Research and Practice",
issn = "1687-6105",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Psoriasis and cardiovascular risk: Assessment by cuore project risk score in Italian patients

AU - Doukaki, S.

AU - Bongiorno, Maria Rita

AU - Caputo, Valentina

PY - 2013

Y1 - 2013

N2 - Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whethewhere cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients. Objective. The objective of this study was to estimate cardiovascular risk score in psoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUORE project risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate of coronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other than psoriasis was performed. CUORE project risk score was higher in patients than controls (6.80 6.34 versus 4.48 4.38, < 0.001). Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was not related to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted.

AB - Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whethewhere cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients. Objective. The objective of this study was to estimate cardiovascular risk score in psoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUORE project risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate of coronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other than psoriasis was performed. CUORE project risk score was higher in patients than controls (6.80 6.34 versus 4.48 4.38, < 0.001). Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was not related to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted.

UR - http://hdl.handle.net/10447/83664

M3 - Article

VL - 2013

SP - 1

EP - 6

JO - Dermatology Research and Practice

JF - Dermatology Research and Practice

SN - 1687-6105

ER -