PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients

Rosalinda Allegro, Anna Martorana, Darvinio Melloni, Vincenzo Serretta, Rosalinda Allegro, Angela Catanese, Raimondo Liotta

Risultato della ricerca: Article

31 Citazioni (Scopus)

Abstract

Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.
Lingua originaleEnglish
pagine (da-a)148-152
Numero di pagine5
RivistaProstate Cancer and Prostatic Diseases
Volume11
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

  • Oncology
  • Urology
  • Cancer Research

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