Abstract
Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.
| Lingua originale | English |
|---|---|
| pagine (da-a) | 148-152 |
| Numero di pagine | 5 |
| Rivista | Prostate Cancer and Prostatic Diseases |
| Volume | 11 |
| Stato di pubblicazione | Published - 2008 |
All Science Journal Classification (ASJC) codes
- Oncology
- Urology
- Cancer Research
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Allegro, R., Martorana, A., Melloni, D., Serretta, V., Allegro, R., Catanese, A., & Liotta, R. (2008). PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients. Prostate Cancer and Prostatic Diseases, 11, 148-152.