PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients

Anna Martorana; Rosalinda Allegro; Darvinio Melloni; Vincenzo Serretta; Rosalinda Allegro; null Allegro; Angela Catanese; Raimondo Liotta

PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients

Anna Martorana, Rosalinda Allegro, Darvinio Melloni, Vincenzo Serretta, Rosalinda Allegro, Allegro, Angela Catanese, Raimondo Liotta

Risultato della ricerca: Article › peer review

33 Citazioni (Scopus)

Abstract

Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.

Lingua originale	English
pagine (da-a)	148-152
Numero di pagine	5
Rivista	Prostate Cancer and Prostatic Diseases
Volume	11
Stato di pubblicazione	Published - 2008

All Science Journal Classification (ASJC) codes

Oncology
Urology
Cancer Research

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title = "PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients",

abstract = "Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.",

keywords = "prostate carcinoma, prostate-specific antigen (PSA), prostatitis, prostate carcinoma, prostate-specific antigen (PSA), prostatitis",

author = "Anna Martorana and Rosalinda Allegro and Darvinio Melloni and Vincenzo Serretta and Rosalinda Allegro and Allegro and Angela Catanese and Raimondo Liotta",

year = "2008",

language = "English",

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T1 - PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients

AU - Martorana, Anna

AU - Allegro, Rosalinda

AU - Melloni, Darvinio

AU - Serretta, Vincenzo

AU - Allegro, Rosalinda

AU - Allegro, null

AU - Catanese, Angela

AU - Liotta, Raimondo

PY - 2008

Y1 - 2008

N2 - Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.

AB - Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.

KW - prostate carcinoma

KW - prostate-specific antigen (PSA)

KW - prostatitis

KW - prostate carcinoma

KW - prostate-specific antigen (PSA)

KW - prostatitis

UR - http://hdl.handle.net/10447/47165

M3 - Article

VL - 11

SP - 148

EP - 152

JO - Prostate Cancer and Prostatic Diseases

JF - Prostate Cancer and Prostatic Diseases

SN - 1365-7852

ER -