Proteomics to elucidate the molecular physiology of Microbispora sp. ATCC-PTA-5024, the producer of NAI-107, a very promising lantibiotic

Teresa Faddetta; Giovanni Spinelli; Rosa Alduina; Anna Maria Puglia; Emilia Palazzotto; Fabio Sangiorgi; Giovanni Renzone

Proteomics to elucidate the molecular physiology of Microbispora sp. ATCC-PTA-5024, the producer of NAI-107, a very promising lantibiotic

Teresa Faddetta, Giovanni Spinelli, Rosa Alduina, Anna Maria Puglia, Emilia Palazzotto, Fabio Sangiorgi, Giovanni Renzone

Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche

Risultato della ricerca: Other › peer review

Abstract

The filamentous actinobacterium Microbispora sp. ATCC-PTA-5024 produces the lantibiotic NAI-107 (Maffioli et al., 2014), which is effective against multidrug-resistant Gram-positive pathogens (Jabés et al., 2011).In actinomycetes, the biosynthesis of antibiotics is generally elicited as a physiological response controlled by a complex regulatory network involving global regulators, playing pleiotropic roles, and pathway-specific regulators, which activate the biosynthesis of biologically active molecules (Bibb, 2005)

Lingua originale	English
Numero di pagine	1
Stato di pubblicazione	Published - 2015

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title = "Proteomics to elucidate the molecular physiology of Microbispora sp. ATCC-PTA-5024, the producer of NAI-107, a very promising lantibiotic",

abstract = "The filamentous actinobacterium Microbispora sp. ATCC-PTA-5024 produces the lantibiotic NAI-107 (Maffioli et al., 2014), which is effective against multidrug-resistant Gram-positive pathogens (Jab{\'e}s et al., 2011).In actinomycetes, the biosynthesis of antibiotics is generally elicited as a physiological response controlled by a complex regulatory network involving global regulators, playing pleiotropic roles, and pathway-specific regulators, which activate the biosynthesis of biologically active molecules (Bibb, 2005)",

author = "Teresa Faddetta and Giovanni Spinelli and Rosa Alduina and Puglia, {Anna Maria} and Emilia Palazzotto and Fabio Sangiorgi and Giovanni Renzone",

year = "2015",

language = "English",

}

TY - CONF

T1 - Proteomics to elucidate the molecular physiology of Microbispora sp. ATCC-PTA-5024, the producer of NAI-107, a very promising lantibiotic

AU - Faddetta, Teresa

AU - Spinelli, Giovanni

AU - Alduina, Rosa

AU - Puglia, Anna Maria

AU - Palazzotto, Emilia

AU - Sangiorgi, Fabio

AU - Renzone, Giovanni

PY - 2015

Y1 - 2015

N2 - The filamentous actinobacterium Microbispora sp. ATCC-PTA-5024 produces the lantibiotic NAI-107 (Maffioli et al., 2014), which is effective against multidrug-resistant Gram-positive pathogens (Jabés et al., 2011).In actinomycetes, the biosynthesis of antibiotics is generally elicited as a physiological response controlled by a complex regulatory network involving global regulators, playing pleiotropic roles, and pathway-specific regulators, which activate the biosynthesis of biologically active molecules (Bibb, 2005)

AB - The filamentous actinobacterium Microbispora sp. ATCC-PTA-5024 produces the lantibiotic NAI-107 (Maffioli et al., 2014), which is effective against multidrug-resistant Gram-positive pathogens (Jabés et al., 2011).In actinomycetes, the biosynthesis of antibiotics is generally elicited as a physiological response controlled by a complex regulatory network involving global regulators, playing pleiotropic roles, and pathway-specific regulators, which activate the biosynthesis of biologically active molecules (Bibb, 2005)

UR - http://hdl.handle.net/10447/253830

M3 - Other

ER -