Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery

Risultato della ricerca: Article

Abstract

The onset of postoperative septic complications has recently been associated to serum levels of interleukin (IL) IL-6 and IL-10. Patients with complications have higher serum levels than patients without complication after surgery. IL-6 has been recognized as early marker of postoperative septic events. Furthermore IL-6 increases with age, expecially if there are associated diseases. It is a sign of functional deterioration of different organs. The disregulation in interleukin production, anesthetic drugs, hemorrhage and transfusions may lead to the onset of postoperative complications. The latter are more frequent in oncologic patients. The aim of our study is to evaluate pre- and postoperative profile of some inflammatory markers (IL-6, IL-10 and Creactive protein CRP) and immunonutritional assessment (through albumin serum levels and lymphocyte count) in a group of elderly patients undergone to major intrabdominal surgery. We related the data obtained to the onset of postoperative complications.
Lingua originaleEnglish
pagine (da-a)1-2
Numero di pagine2
RivistaBMC Geriatrics
VolumeA92
Stato di pubblicazionePublished - 2009

Fingerprint

Geriatrics
Interleukin-10
Interleukin-6
Interleukins
Serum
Lymphocyte Count
Serum Albumin
Hemorrhage

Cita questo

@article{093039c46cee4e79b09b5c541b31f481,
title = "Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery",
abstract = "The onset of postoperative septic complications has recently been associated to serum levels of interleukin (IL) IL-6 and IL-10. Patients with complications have higher serum levels than patients without complication after surgery. IL-6 has been recognized as early marker of postoperative septic events. Furthermore IL-6 increases with age, expecially if there are associated diseases. It is a sign of functional deterioration of different organs. The disregulation in interleukin production, anesthetic drugs, hemorrhage and transfusions may lead to the onset of postoperative complications. The latter are more frequent in oncologic patients. The aim of our study is to evaluate pre- and postoperative profile of some inflammatory markers (IL-6, IL-10 and Creactive protein CRP) and immunonutritional assessment (through albumin serum levels and lymphocyte count) in a group of elderly patients undergone to major intrabdominal surgery. We related the data obtained to the onset of postoperative complications.",
keywords = "pre- and postoperative profile of some inflammatory markers",
author = "Giuseppe Diana and Cudia, {Bianca Maria} and Giovanni Guercio and Ricotta, {Calogero Antonio Carmelo} and Francesco Bavetta and Balistreri, {Carmela Rita}",
year = "2009",
language = "English",
volume = "A92",
pages = "1--2",
journal = "BMC Geriatrics",
issn = "1471-2318",
publisher = "BioMed Central",

}

TY - JOUR

T1 - Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery

AU - Diana, Giuseppe

AU - Cudia, Bianca Maria

AU - Guercio, Giovanni

AU - Ricotta, Calogero Antonio Carmelo

AU - Bavetta, Francesco

AU - Balistreri, Carmela Rita

PY - 2009

Y1 - 2009

N2 - The onset of postoperative septic complications has recently been associated to serum levels of interleukin (IL) IL-6 and IL-10. Patients with complications have higher serum levels than patients without complication after surgery. IL-6 has been recognized as early marker of postoperative septic events. Furthermore IL-6 increases with age, expecially if there are associated diseases. It is a sign of functional deterioration of different organs. The disregulation in interleukin production, anesthetic drugs, hemorrhage and transfusions may lead to the onset of postoperative complications. The latter are more frequent in oncologic patients. The aim of our study is to evaluate pre- and postoperative profile of some inflammatory markers (IL-6, IL-10 and Creactive protein CRP) and immunonutritional assessment (through albumin serum levels and lymphocyte count) in a group of elderly patients undergone to major intrabdominal surgery. We related the data obtained to the onset of postoperative complications.

AB - The onset of postoperative septic complications has recently been associated to serum levels of interleukin (IL) IL-6 and IL-10. Patients with complications have higher serum levels than patients without complication after surgery. IL-6 has been recognized as early marker of postoperative septic events. Furthermore IL-6 increases with age, expecially if there are associated diseases. It is a sign of functional deterioration of different organs. The disregulation in interleukin production, anesthetic drugs, hemorrhage and transfusions may lead to the onset of postoperative complications. The latter are more frequent in oncologic patients. The aim of our study is to evaluate pre- and postoperative profile of some inflammatory markers (IL-6, IL-10 and Creactive protein CRP) and immunonutritional assessment (through albumin serum levels and lymphocyte count) in a group of elderly patients undergone to major intrabdominal surgery. We related the data obtained to the onset of postoperative complications.

KW - pre- and postoperative profile of some inflammatory markers

UR - http://hdl.handle.net/10447/46618

M3 - Article

VL - A92

SP - 1

EP - 2

JO - BMC Geriatrics

JF - BMC Geriatrics

SN - 1471-2318

ER -