Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery

Risultato della ricerca: Article

Abstract

The onset of postoperative septic complications hasrecently been associated to serum levels of interleukin (IL)IL-6 and IL-10. Patients with complications have higherserum levels than patients without complication after surgery.IL-6 has been recognized as early marker of postoperativeseptic events. Furthermore IL-6 increases with age,expecially if there are associated diseases. It is a sign offunctional deterioration of different organs.The disregulation in interleukin production, anestheticdrugs, hemorrhage and transfusions may lead to the onsetof postoperative complications. The latter are more frequentin oncologic patients.The aim of our study is to evaluate pre- and postoperativeprofile of some inflammatory markers (IL-6, IL-10 and Creactiveprotein CRP) and immunonutritional assessment(through albumin serum levels and lymphocyte count) ina group of elderly patients undergone to major intrabdominalsurgery. We related the data obtained to theonset of postoperative complications.
Lingua originaleEnglish
pagine (da-a)1-2
Numero di pagine2
RivistaBMC Geriatrics
VolumeA92
Stato di pubblicazionePublished - 2009

Fingerprint

Geriatrics
Interleukin-10
Interleukin-6
Interleukins
Serum
Lymphocyte Count
Serum Albumin
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Geriatrics and Gerontology

Cita questo

@article{093039c46cee4e79b09b5c541b31f481,
title = "Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery",
abstract = "The onset of postoperative septic complications hasrecently been associated to serum levels of interleukin (IL)IL-6 and IL-10. Patients with complications have higherserum levels than patients without complication after surgery.IL-6 has been recognized as early marker of postoperativeseptic events. Furthermore IL-6 increases with age,expecially if there are associated diseases. It is a sign offunctional deterioration of different organs.The disregulation in interleukin production, anestheticdrugs, hemorrhage and transfusions may lead to the onsetof postoperative complications. The latter are more frequentin oncologic patients.The aim of our study is to evaluate pre- and postoperativeprofile of some inflammatory markers (IL-6, IL-10 and Creactiveprotein CRP) and immunonutritional assessment(through albumin serum levels and lymphocyte count) ina group of elderly patients undergone to major intrabdominalsurgery. We related the data obtained to theonset of postoperative complications.",
keywords = "pre- and postoperative profile of some inflammatory markers",
author = "Ricotta, {Calogero Antonio Carmelo} and Giuseppe Diana and Giovanni Guercio and Cudia, {Bianca Maria} and Balistreri, {Carmela Rita} and Francesco Bavetta",
year = "2009",
language = "English",
volume = "A92",
pages = "1--2",
journal = "BMC Geriatrics",
issn = "1471-2318",
publisher = "BioMed Central",

}

TY - JOUR

T1 - Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery

AU - Ricotta, Calogero Antonio Carmelo

AU - Diana, Giuseppe

AU - Guercio, Giovanni

AU - Cudia, Bianca Maria

AU - Balistreri, Carmela Rita

AU - Bavetta, Francesco

PY - 2009

Y1 - 2009

N2 - The onset of postoperative septic complications hasrecently been associated to serum levels of interleukin (IL)IL-6 and IL-10. Patients with complications have higherserum levels than patients without complication after surgery.IL-6 has been recognized as early marker of postoperativeseptic events. Furthermore IL-6 increases with age,expecially if there are associated diseases. It is a sign offunctional deterioration of different organs.The disregulation in interleukin production, anestheticdrugs, hemorrhage and transfusions may lead to the onsetof postoperative complications. The latter are more frequentin oncologic patients.The aim of our study is to evaluate pre- and postoperativeprofile of some inflammatory markers (IL-6, IL-10 and Creactiveprotein CRP) and immunonutritional assessment(through albumin serum levels and lymphocyte count) ina group of elderly patients undergone to major intrabdominalsurgery. We related the data obtained to theonset of postoperative complications.

AB - The onset of postoperative septic complications hasrecently been associated to serum levels of interleukin (IL)IL-6 and IL-10. Patients with complications have higherserum levels than patients without complication after surgery.IL-6 has been recognized as early marker of postoperativeseptic events. Furthermore IL-6 increases with age,expecially if there are associated diseases. It is a sign offunctional deterioration of different organs.The disregulation in interleukin production, anestheticdrugs, hemorrhage and transfusions may lead to the onsetof postoperative complications. The latter are more frequentin oncologic patients.The aim of our study is to evaluate pre- and postoperativeprofile of some inflammatory markers (IL-6, IL-10 and Creactiveprotein CRP) and immunonutritional assessment(through albumin serum levels and lymphocyte count) ina group of elderly patients undergone to major intrabdominalsurgery. We related the data obtained to theonset of postoperative complications.

KW - pre- and postoperative profile of some inflammatory markers

UR - http://hdl.handle.net/10447/46618

M3 - Article

VL - A92

SP - 1

EP - 2

JO - BMC Geriatrics

JF - BMC Geriatrics

SN - 1471-2318

ER -