Probing in cell protein structural changes with time-resolved X-ray scattering

Giorgio Schiro'; Matteo Levantino; Antonio Cupane; Michael Wulff; Marco Cammarata; Alessandro Spilotros

Probing in cell protein structural changes with time-resolved X-ray scattering

Giorgio Schiro', Matteo Levantino, Antonio Cupane, Michael Wulff, Marco Cammarata, Alessandro Spilotros

Fisica e Chimica - Emilio Segrè

Risultato della ricerca: Article › peer review

9 Citazioni (Scopus)

Abstract

Investigating protein structural changes inside the cell is a major goal in molecular biology. Here we show that time-resolved wide-angle X-ray scattering is a valuable tool for this purpose. Hemoglobin has been chosen as a model system and its tertiary and quaternary conformational changes following laser flash-photolysis have been tracked in intact red blood cells with nanosecond time resolution.

Lingua originale	English
pagine (da-a)	6434-6437
Numero di pagine	4
Rivista	Soft Matter
Volume	8
Stato di pubblicazione	Published - 2012

All Science Journal Classification (ASJC) codes

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???subjectarea.asjc.3100.3104???

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title = "Probing in cell protein structural changes with time-resolved X-ray scattering",

abstract = "Investigating protein structural changes inside the cell is a major goal in molecular biology. Here we show that time-resolved wide-angle X-ray scattering is a valuable tool for this purpose. Hemoglobin has been chosen as a model system and its tertiary and quaternary conformational changes following laser flash-photolysis have been tracked in intact red blood cells with nanosecond time resolution.",

author = "Giorgio Schiro' and Matteo Levantino and Antonio Cupane and Michael Wulff and Marco Cammarata and Alessandro Spilotros",

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language = "English",

volume = "8",

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journal = "Soft Matter",

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TY - JOUR

T1 - Probing in cell protein structural changes with time-resolved X-ray scattering

AU - Schiro', Giorgio

AU - Levantino, Matteo

AU - Cupane, Antonio

AU - Wulff, Michael

AU - Cammarata, Marco

AU - Spilotros, Alessandro

PY - 2012

Y1 - 2012

N2 - Investigating protein structural changes inside the cell is a major goal in molecular biology. Here we show that time-resolved wide-angle X-ray scattering is a valuable tool for this purpose. Hemoglobin has been chosen as a model system and its tertiary and quaternary conformational changes following laser flash-photolysis have been tracked in intact red blood cells with nanosecond time resolution.

AB - Investigating protein structural changes inside the cell is a major goal in molecular biology. Here we show that time-resolved wide-angle X-ray scattering is a valuable tool for this purpose. Hemoglobin has been chosen as a model system and its tertiary and quaternary conformational changes following laser flash-photolysis have been tracked in intact red blood cells with nanosecond time resolution.

UR - http://hdl.handle.net/10447/63231

UR - http://pubs.rsc.org/en/content/articlelanding/2012/sm/c2sm25676b

M3 - Article

VL - 8

SP - 6434

EP - 6437

JO - Soft Matter

JF - Soft Matter

SN - 1744-683X

ER -

Probing in cell protein structural changes with time-resolved X-ray scattering

Abstract

All Science Journal Classification (ASJC) codes

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