Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

Francesco Ciccia, Laura Saieva, Riccardo Alessandro, Giuliana Guggino, Francesco Dieli, Laura Saieva, Nigil Haroon, Ranjeny Thomas, Vidya Ranganathan, Arifur Rahman, Francesco Dieli, Michael Zeng, Arifur Rahman, Diana Di Liberto, Riccardo Alessandro, Dominique Baeten, Roberto Giacomelli, Paola Cipriani, Diana Di Liberto

Risultato della ricerca: Article

4 Citazioni (Scopus)

Abstract

Gut derived ILC3 have been demonstrated to participate in AS pathogenesis. CX3CR1+ mononuclear phagocytes (MNP) have been demonstrated to modulate ILC3 function in the gut. The aim of this study was to study the role of pro-inflammatory CX3CR1+ CD59+ MNP in modulating ILC3 function in AS patients.
Lingua originaleEnglish
Numero di pagine15
RivistaARTHRITIS & RHEUMATOLOGY
Stato di pubblicazionePublished - 2018

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Interleukin-23
Ankylosing Spondylitis
Phagocytes
Monocytes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Rheumatology
  • Immunology

Cita questo

Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions. / Ciccia, Francesco; Saieva, Laura; Alessandro, Riccardo; Guggino, Giuliana; Dieli, Francesco; Saieva, Laura; Haroon, Nigil; Thomas, Ranjeny; Ranganathan, Vidya; Rahman, Arifur; Dieli, Francesco; Zeng, Michael; Rahman, Arifur; Di Liberto, Diana; Alessandro, Riccardo; Baeten, Dominique; Giacomelli, Roberto; Cipriani, Paola; Di Liberto, Diana.

In: ARTHRITIS & RHEUMATOLOGY, 2018.

Risultato della ricerca: Article

Ciccia, F, Saieva, L, Alessandro, R, Guggino, G, Dieli, F, Saieva, L, Haroon, N, Thomas, R, Ranganathan, V, Rahman, A, Dieli, F, Zeng, M, Rahman, A, Di Liberto, D, Alessandro, R, Baeten, D, Giacomelli, R, Cipriani, P & Di Liberto, D 2018, 'Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions', ARTHRITIS & RHEUMATOLOGY.
Ciccia, Francesco ; Saieva, Laura ; Alessandro, Riccardo ; Guggino, Giuliana ; Dieli, Francesco ; Saieva, Laura ; Haroon, Nigil ; Thomas, Ranjeny ; Ranganathan, Vidya ; Rahman, Arifur ; Dieli, Francesco ; Zeng, Michael ; Rahman, Arifur ; Di Liberto, Diana ; Alessandro, Riccardo ; Baeten, Dominique ; Giacomelli, Roberto ; Cipriani, Paola ; Di Liberto, Diana. / Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions. In: ARTHRITIS & RHEUMATOLOGY. 2018.
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title = "Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions",
abstract = "Gut derived ILC3 have been demonstrated to participate in AS pathogenesis. CX3CR1+ mononuclear phagocytes (MNP) have been demonstrated to modulate ILC3 function in the gut. The aim of this study was to study the role of pro-inflammatory CX3CR1+ CD59+ MNP in modulating ILC3 function in AS patients.",
keywords = "CX3CR1+ monocytes, IL-23, ILC3, TL1A, gut inflammation",
author = "Francesco Ciccia and Laura Saieva and Riccardo Alessandro and Giuliana Guggino and Francesco Dieli and Laura Saieva and Nigil Haroon and Ranjeny Thomas and Vidya Ranganathan and Arifur Rahman and Francesco Dieli and Michael Zeng and Arifur Rahman and {Di Liberto}, Diana and Riccardo Alessandro and Dominique Baeten and Roberto Giacomelli and Paola Cipriani and {Di Liberto}, Diana",
year = "2018",
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T1 - Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

AU - Ciccia, Francesco

AU - Saieva, Laura

AU - Alessandro, Riccardo

AU - Guggino, Giuliana

AU - Dieli, Francesco

AU - Saieva, Laura

AU - Haroon, Nigil

AU - Thomas, Ranjeny

AU - Ranganathan, Vidya

AU - Rahman, Arifur

AU - Dieli, Francesco

AU - Zeng, Michael

AU - Rahman, Arifur

AU - Di Liberto, Diana

AU - Alessandro, Riccardo

AU - Baeten, Dominique

AU - Giacomelli, Roberto

AU - Cipriani, Paola

AU - Di Liberto, Diana

PY - 2018

Y1 - 2018

N2 - Gut derived ILC3 have been demonstrated to participate in AS pathogenesis. CX3CR1+ mononuclear phagocytes (MNP) have been demonstrated to modulate ILC3 function in the gut. The aim of this study was to study the role of pro-inflammatory CX3CR1+ CD59+ MNP in modulating ILC3 function in AS patients.

AB - Gut derived ILC3 have been demonstrated to participate in AS pathogenesis. CX3CR1+ mononuclear phagocytes (MNP) have been demonstrated to modulate ILC3 function in the gut. The aim of this study was to study the role of pro-inflammatory CX3CR1+ CD59+ MNP in modulating ILC3 function in AS patients.

KW - CX3CR1+ monocytes

KW - IL-23

KW - ILC3

KW - TL1A

KW - gut inflammation

UR - http://hdl.handle.net/10447/295625

M3 - Article

JO - ARTHRITIS & RHEUMATOLOGY

JF - ARTHRITIS & RHEUMATOLOGY

SN - 2326-5191

ER -