Abstract
| Lingua originale | English |
|---|---|
| pagine (da-a) | 00- |
| Numero di pagine | 6 |
| Rivista | BMC Research Notes |
| Volume | 11 |
| Stato di pubblicazione | Published - 2018 |
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All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
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Predictors of therapy failure in newly diagnosed pulmonary tuberculosis cases in Beira, Mozambique. / Mazzucco, Walter; Marotta, Claudia; Saracino, Annalisa; Monno, Laura; Putoto, Giovanni; Chhaganlal, Kajal; Pizzol, Damiano; Veronese, Nicola; Di Gennaro, Francesco; Moiane, Jorge.
In: BMC Research Notes, Vol. 11, 2018, pag. 00-.Risultato della ricerca: Article
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TY - JOUR
T1 - Predictors of therapy failure in newly diagnosed pulmonary tuberculosis cases in Beira, Mozambique
AU - Mazzucco, Walter
AU - Marotta, Claudia
AU - Saracino, Annalisa
AU - Monno, Laura
AU - Putoto, Giovanni
AU - Chhaganlal, Kajal
AU - Pizzol, Damiano
AU - Veronese, Nicola
AU - Di Gennaro, Francesco
AU - Moiane, Jorge
PY - 2018
Y1 - 2018
N2 - Objective: Tuberculosis (TB) remains a major global health issue, ranking in the top ten causes of death worldwide. A deep understanding of factors in uencing poor treatment outcomes may allow the development of additional treatment strategies, focused on the most vulnerable groups. Aims of the study were: (i) to evaluate the treatment outcome among TB subjects followed in an outpatient setting and (ii) to analyze factors associated with treatment failure in newly diagnosed patients with pulmonary TB in Beira, the second largest city of Mozambique. Results: A total of 301 TB adult patients (32.6% females) were enrolled. Among them, 62 (20.6%) experienced a treat- ment failure over a 6 months follow-up. On multivariate model, being males (O.R. = 1.73; 95% CI 1.28–2.15), absence of education (O.R. = 1.85; 95% CI 1.02–2.95), monthly income under 50 dollars (O.R. = 1.74; 95% CI 1.24–2.21) and being employed (O.R. = 1.57; 95% CI 1.21–1.70), low body mass index values (O.R. = 1.42; 95% CI 1.18–1.72) and HIV status (O.R. = 1.42; 95% CI 1.10–1.78) increased the likelihood of therapy failure over 6 months of follow-up. In this study, patients who need more medical attention were young males, malnourished, with low income and low educa- tional degree and HIV positive. These subjects were more likely to fail therapy.
AB - Objective: Tuberculosis (TB) remains a major global health issue, ranking in the top ten causes of death worldwide. A deep understanding of factors in uencing poor treatment outcomes may allow the development of additional treatment strategies, focused on the most vulnerable groups. Aims of the study were: (i) to evaluate the treatment outcome among TB subjects followed in an outpatient setting and (ii) to analyze factors associated with treatment failure in newly diagnosed patients with pulmonary TB in Beira, the second largest city of Mozambique. Results: A total of 301 TB adult patients (32.6% females) were enrolled. Among them, 62 (20.6%) experienced a treat- ment failure over a 6 months follow-up. On multivariate model, being males (O.R. = 1.73; 95% CI 1.28–2.15), absence of education (O.R. = 1.85; 95% CI 1.02–2.95), monthly income under 50 dollars (O.R. = 1.74; 95% CI 1.24–2.21) and being employed (O.R. = 1.57; 95% CI 1.21–1.70), low body mass index values (O.R. = 1.42; 95% CI 1.18–1.72) and HIV status (O.R. = 1.42; 95% CI 1.10–1.78) increased the likelihood of therapy failure over 6 months of follow-up. In this study, patients who need more medical attention were young males, malnourished, with low income and low educa- tional degree and HIV positive. These subjects were more likely to fail therapy.
UR - http://hdl.handle.net/10447/279325
M3 - Article
VL - 11
SP - 00-
JO - BMC Research Notes
JF - BMC Research Notes
SN - 1756-0500
ER -