Predictors of insulin resistance in patients with obesity: a pilot study.

Manfredi Rizzo, Maciej Banach, Rafał N. Wlazeł, Mariusz Stȩpień, Marek Paradowski, Jacek Rysz, Anna Stȩpień, Manfredi Rizzo

Risultato della ricerca: Articlepeer review

32 Citazioni (Scopus)

Abstract

We compared adipokines and inflammatory markers in obese insulin-sensitive (group A, n ¼ 16) and insulin-resistant (group B,n ¼ 48) patients divided according to homeostasis model assessment of insulin resistance (HOMA-IR). Serum levels ofadiponectin, leptin, resistin, high-sensitivity C-reactive protein, interleukin 6, and tumor necrosis factor a were measured.Weight, height, waist (WC) and hip circumferences, waist to hip ratio , weight to height ratio, visceral adiposity index (VAI), andbody adiposity index (BAI) were measured. The WC and VAI were significantly higher in group B (113.9 + 11.1 vs105.3 + 9.8cm; P < .01 and 2.3 + 1.1 vs 1.6 + 0.9; P < .05, respectively), while serum adiponectin levels were higher in groupA (24.5 + 14.6 vs 15.1 + 9.6 ng/mL; P < .005). The BAI strongly correlated with adiponectin and leptin in group B (r = .479;P < .001 and r = .705; P < .001). Insulin resistance is associated with visceral adiposity described by VAI and WC. The BAI maybe a useful index in obese patients, especially with insulin resistance.
Lingua originaleEnglish
pagine (da-a)22-30
Numero di pagine9
RivistaAngiology
Volume65
Stato di pubblicazionePublished - 2014

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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