"Positive biology": thecentenarian lesson.

Calogero Caruso, Giovanni Scapagnini, Annibale Puca, Giuseppe Passarino

Risultato della ricerca: Articlepeer review

26 Citazioni (Scopus)


The extraordinary increase of the elderly in developed countries underscore the importance of studies on ageingand longevity and the need for the prompt spread of knowledge about ageing in order to satisfactorily decreasethe medical, economic and social problems associated to advancing years, because of the increased number ofindividuals not autonomous and affected by invalidating pathologies.Centenarians are equipped to reach the extreme limits of human life span and, most importantly, to show relativelygood health, being able to perform their routine daily life and to escape fatal age-related diseases. Thus, they arethe best example of extreme longevity, representing selected people in which the appearance of major age-relateddiseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. Todiscuss the relevance of genetics and life style in the attainment of longevity, five papers mostly focused on Italiancentenarians have been assembled in this series. The aim is to realize, through a” positive biology” approach (ratherthan making diseases the central focus of research, “positive biology” seeks to understand the causes of positivephenotypes, trying to explain the biological mechanisms of health and well-being) how to prevent and/or reduceelderly frailty and disability.
Lingua originaleEnglish
Numero di pagine0
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Immunology
  • Ageing

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