Porphyromonas gingivalis, Periodontal and Systemic Implications: A Systematic Review

Rodolfo Mauceri, Marco Cicciù, Luigi Laino, Gabriele Cervino, Tolga Fikret Tozum, Luca Fiorillo, Cesare D'Amico, Cesare D'Amico, Michele Gaeta

Risultato della ricerca: Articlepeer review

34 Citazioni (Scopus)


In recent scientific literature, oral infections and systemic manifestations, or correlations between oral health and systemic diseases are a topic of discussion. Porphyromonas gingivalis is one of the bacteria implicated in the biofilm formation of bacterial plaque, and plays an important role in the progression of periodontal disease. In this systematic review authors have evaluated the literature of the last 10 years on P. gingivalis and all the systemic implications proven. This study therefore evaluates all the districts of the organism in which this bacterium may have implications. From the results it emerges that P. gingivalis has implications in the onset of different systemic pathologies, including rheumatoid arthritis, cardiovascular pathologies, and neurodegenerative pathologies. Surely, understanding the mechanisms of diffusion of this bacterium, it would be possible to prevent a series of pathologies. Thus, putting the dentist clinician at the center of prevention for these diseases.
Lingua originaleEnglish
pagine (da-a)114-
Numero di pagine15
RivistaDentistry Journal
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

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