Background: The oxidative stress results from a change in the physiological balancebetween oxidant and antioxidant species. The purpose of this study is twofold: first, to investigatethe effects of long-term training in sports with high energy requirements on the redox balancewhich exists between the plasma vs. the erythrocytes; second, to study the activity of the PMRS(Plasma Membrane Redox System), which is a compensatory mechanism of cellular redoxhomeostasis, in the rowers’ erythrocytes in order to determine the rowers’ counteraction tooxidative stress.Methods: Venous blood samples was collected from rowers and control group; then FRAP(Ferric Reducing Activity Power) method has been used to determine the antioxidant capabilitiesboth in the plasma and in the erythrocytes of 22 rowers vs. 26 sedentary subjects. For the samegroups of subjects, the PMRS in erythrocytes has been also evaluated.Results: The plasmatic antioxidant activity was 21% lower in the group of rowers comparedto the sedentary group (p = 0,02). In contrast, no significant differences were found in the reducingactivity of the erythrocytes; however the erythrocytes of the rowers have shown values of thePMRS 35% higher than the untrained group (p < 0.0001).Conclusions: Rowing induces a significant oxidative stress in the plasma corresponding tothe high intensity training, while this effect lacks in erythrocytes. At the same time an increasedquantity of the PMRS has been observed in the erythrocytes. In conclusion, in well trained athletesthis not lead to established an oxidative stress condition because long-term training adaptativelyimproves the efficiency of the antioxidant system
Lingua originaleEnglish
Titolo della pubblicazione ospite58° National meeting of the Italian Society of Biochemestry and Molecular Biology
Numero di pagine1
Stato di pubblicazionePublished - 2015


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