Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: relationship with TOAST subtype, outcome and infarct site

Risultato della ricerca: Articlepeer review

62 Citazioni (Scopus)

Abstract

BACKGROUND:The aim of our study was to evaluate in patients with acute ischemic stroke the relationship between immuno-inflammatory variables, clinical outcome and infarct site.MATERIALS AND METHODS:We evaluated plasma levels of IL-1beta, TNF-alpha, IL-6 and IL-10, E-selectin, P-selectin, sICAM-1 ,sVCAM-1 vWF, TPA and PAI-1.RESULTS:Patients with cardioembolic subtype showed significantly higher median plasma levels of TNF-alpha, IL-6, IL-1beta whereas the lacunar subtype showed significantly lower median plasma levels of TNF-alpha, IL-6 and IL-1beta.CONCLUSIONS:A significant association was noted between the severity of neurological deficit at admission, the diagnostic subtype and some inflammatory variables.
Lingua originaleEnglish
pagine (da-a)84-89
Numero di pagine6
RivistaJournal of Neuroimmunology
Volume21
Stato di pubblicazionePublished - 2009

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Neurology
  • Clinical Neurology

Fingerprint Entra nei temi di ricerca di 'Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: relationship with TOAST subtype, outcome and infarct site'. Insieme formano una fingerprint unica.

Cita questo