Phytochemical and anti‑staphylococcal biofilm assessment of Dracaena draco L. Spp. draco resin

Risultato della ricerca: Article

13 Citazioni (Scopus)

Abstract

Background: Dracaena draco L. ssp. draco is known as the “dragon’s blood tree” and it is endemic from the Canary Islands and Morocco. Objective: Carry out phytochemical investigation of acetonic extracts of red resin obtained from the trunk of D. draco, to obtain to the isolation of the most abundant resin constituents, belonging to the class of flavonoids: flavans, along with homoisoflavans and homoisoflavanones. Materials and Methods: The structures of the isolated compounds were established by Nuclear Magnetic Resonance (NMR) and mass spectrometry data and comparison with literature data. The acetonic extract was evaluated for its anti‑staphylococcal properties against two reference strains. Results: The acetonic extracts resulted inactive at the maximum tested concentration of 1000 μg/ml against free living forms of tested staphylococci, but they showed a very interesting activity in the prevention of a biofilm formation at a concentration equal to 200 μg/ml against S. aureus ATCC 25923.
Lingua originaleEnglish
pagine (da-a)434-440
Numero di pagine7
RivistaPharmacognosy Magazine
Volume10
Stato di pubblicazionePublished - 2014

Fingerprint

Dracaena
Dracaena draco
Morocco
Phytochemicals
Biofilms
Staphylococcus
Flavonoids
Spain
phytopharmaceuticals
resins
Mass Spectrometry
Magnetic Resonance Spectroscopy
extracts
Canary Islands
biofilm
nuclear magnetic resonance spectroscopy
flavonoids
mass spectrometry
blood
dragon's blood

All Science Journal Classification (ASJC) codes

  • Food Science

Cita questo

@article{7fafdc3b34084b2cb4aaf96d5f86e149,
title = "Phytochemical and anti‑staphylococcal biofilm assessment of Dracaena draco L. Spp. draco resin",
abstract = "Background: Dracaena draco L. ssp. draco is known as the “dragon’s blood tree” and it is endemic from the Canary Islands and Morocco. Objective: Carry out phytochemical investigation of acetonic extracts of red resin obtained from the trunk of D. draco, to obtain to the isolation of the most abundant resin constituents, belonging to the class of flavonoids: flavans, along with homoisoflavans and homoisoflavanones. Materials and Methods: The structures of the isolated compounds were established by Nuclear Magnetic Resonance (NMR) and mass spectrometry data and comparison with literature data. The acetonic extract was evaluated for its anti‑staphylococcal properties against two reference strains. Results: The acetonic extracts resulted inactive at the maximum tested concentration of 1000 μg/ml against free living forms of tested staphylococci, but they showed a very interesting activity in the prevention of a biofilm formation at a concentration equal to 200 μg/ml against S. aureus ATCC 25923.",
author = "Domenico Schillaci and {Di Stefano}, Vita and Rosa Pitonzo and Piergiorgio Fuochi",
year = "2014",
language = "English",
volume = "10",
pages = "434--440",
journal = "Pharmacognosy Magazine",
issn = "0973-1296",
publisher = "Medknow Publications and Media Pvt. Ltd",

}

TY - JOUR

T1 - Phytochemical and anti‑staphylococcal biofilm assessment of Dracaena draco L. Spp. draco resin

AU - Schillaci, Domenico

AU - Di Stefano, Vita

AU - Pitonzo, Rosa

AU - Fuochi, Piergiorgio

PY - 2014

Y1 - 2014

N2 - Background: Dracaena draco L. ssp. draco is known as the “dragon’s blood tree” and it is endemic from the Canary Islands and Morocco. Objective: Carry out phytochemical investigation of acetonic extracts of red resin obtained from the trunk of D. draco, to obtain to the isolation of the most abundant resin constituents, belonging to the class of flavonoids: flavans, along with homoisoflavans and homoisoflavanones. Materials and Methods: The structures of the isolated compounds were established by Nuclear Magnetic Resonance (NMR) and mass spectrometry data and comparison with literature data. The acetonic extract was evaluated for its anti‑staphylococcal properties against two reference strains. Results: The acetonic extracts resulted inactive at the maximum tested concentration of 1000 μg/ml against free living forms of tested staphylococci, but they showed a very interesting activity in the prevention of a biofilm formation at a concentration equal to 200 μg/ml against S. aureus ATCC 25923.

AB - Background: Dracaena draco L. ssp. draco is known as the “dragon’s blood tree” and it is endemic from the Canary Islands and Morocco. Objective: Carry out phytochemical investigation of acetonic extracts of red resin obtained from the trunk of D. draco, to obtain to the isolation of the most abundant resin constituents, belonging to the class of flavonoids: flavans, along with homoisoflavans and homoisoflavanones. Materials and Methods: The structures of the isolated compounds were established by Nuclear Magnetic Resonance (NMR) and mass spectrometry data and comparison with literature data. The acetonic extract was evaluated for its anti‑staphylococcal properties against two reference strains. Results: The acetonic extracts resulted inactive at the maximum tested concentration of 1000 μg/ml against free living forms of tested staphylococci, but they showed a very interesting activity in the prevention of a biofilm formation at a concentration equal to 200 μg/ml against S. aureus ATCC 25923.

UR - http://hdl.handle.net/10447/96509

M3 - Article

VL - 10

SP - 434

EP - 440

JO - Pharmacognosy Magazine

JF - Pharmacognosy Magazine

SN - 0973-1296

ER -