Personalized Symptom Goals and Patient Global Impression on Clinical Changes in Advanced Cancer Patients

Andrea Cortegiani, Kyriaki Mystakidou, Claudio Adile, Sebastiano Mercadante, Marta Rosati, Romina Rossi, Luiz Guilherme Soares, Francesco Masedu, Franco Marinangeli, Gaetano Lanzetta, Stefano De Santis, Marco Maltoni, Patrizia Ferrera, Marco Valenti, Federica Aielli, Claudio Adile

Risultato della ricerca: Articlepeer review

5 Citazioni (Scopus)

Abstract

BACKGROUND:The aim of this study was to assess the patients' global impression (PGI) after symptom management, as well as the achievement of personalized symptom goals (PSG). The secondary outcome was to assess related factors. Subjects, Materials, and Methods . Advanced cancer patients admitted to palliative care units rated symptom intensity by using the Edmonton Symptom Assessment Score (ESAS) at admission and then after 1 week. For each symptom, patient-reported PGI and PSG, as well as the rate of PSG response, were evaluated.RESULTS:Eight hundred seventy-six patients were taken into consideration for this study. A mean of 1.71-2.16 points was necessary to perceive a bit better improvement of symptom intensity. Most patients had a PSG of ≤3. A statistically significant number of patients achieved their PSG after starting palliative care. Patients with high intensity of ESAS items at admission achieved a more favorable PGI response. In the multivariate analysis, symptom intensity and PSG were the most frequent factors independently associated to a best PGI, whereas high levels of Karnofsky had a lower odd ratio.CONCLUSION:PSG and PGI seem to be relevant for patients' assessment and decision-making process, translating in terms of therapeutic intervention. Some factors may be implicated in determining the individual target and clinical response.IMPLICATIONS FOR PRACTICE:Personalized symptom goals and global impression of change are relevant for patients' assessment and decision-making process, translating in terms of therapeutic intervention. Some factors may be implicated in determining the individual target and clinical response.
Lingua originaleEnglish
pagine (da-a)1-8
Numero di pagine8
RivistaTHE ONCOLOGIST
Volume23
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.1300.1306???

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