Peritoneal carcinosis of ovarian origin

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Epithelial ovarian cancer (EOC) is the second most commongenital malignancy in women and is the most lethalgynecological malignancy, with an estimated five-yearsurvival rate of 39%. Despite efforts to develop an effectiveovarian cancer screening method, 60% of patients stillpresent with advanced disease. Comprehensive managementusing surgical cytoreduction to decrease the tumorload to a minimum, and intraperitoneal chemotherapy toeliminate microscopic disease on peritoneal surface, hasthe potential to greatly improve quality of life and to havean impact on survival in ovarian cancer patients. Despiteachieving clinical remission after completion of initial treatment,most patients (60%) with advanced EOC will ultimatelydevelop recurrent disease or show drug resistance;the eventual rate of curability is less than 30%. Given thepoor outcome of women with advanced EOC, it is imperativeto continue to explore novel therapies.©
Lingua originaleEnglish
pagine (da-a)102-108
Numero di pagine7
RivistaJournal of Gastrointestinal Oncology
Stato di pubblicazionePublished - 2010


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