Pathophysiology of vascular dementia

Calogero Caruso, Claudia Maria Rizzo, Laura Castiglia, Claudia Rizzo, Francesco Iemolo, Giovanni Duro, Vladimir Hachinski, Calogero Caruso, Laura Castiglia

Risultato della ricerca: Articlepeer review

46 Citazioni (Scopus)


The concept of Vascular Dementia (VaD) has been recognized for over a century, but its definitionand diagnostic criteria remain unclear.Conventional definitions identify the patients too late, miss subjects with cognitive impairmentshort of dementia, and emphasize consequences rather than causes, the true bases for treatmentand prevention. We should throw out current diagnostic categories and describe cognitiveimpairment clinically and according to commonly agreed instruments that document thedemographic data in a standardized manner and undertake a systematic effort to identify theunderlying aetiology in each case.Increased effort should be targeted towards the concept of and criteria for Vascular CognitiveImpairment and Post-Stroke Dementia as well as for genetic factors involved, especially as thesecategories hold promise for early prevention and treatment.
Lingua originaleEnglish
Numero di pagine0
Stato di pubblicazionePublished - 2009

All Science Journal Classification (ASJC) codes

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