PATHOPHYSIOLOGY AND CLINICAL ASPECTS OF URINARY LITHIASIS

Darvinio Melloni, Marco Vella, Giuseppe Coraci, Maria Karydi

Risultato della ricerca: Articlepeer review

10 Citazioni (Scopus)

Abstract

Urine is a complex balanced solution containing dissociated and non-dissociated solutes. Any variation in urine saturation grade (number of crystals dissolved in a volume of urine), urinary pH and the concentration of crystallization inhibitors can break the normal existing balance and lead to urolithiasis. In the present article we analyze the principal mechanisms (absorptive, renal, resorptive) of hypercalciuria. It will be also shown how heredity directly influences the clinical aspects of cystine, xanthine and oxalate lithiasis and how diet, in association with metabolic disorders, interferes in uric acid and oxalate stone formation. Finally, we report on the roles of urinary tract malformations, urinary tract infections and drugs in the clinical characterization of urolithiasis.
Lingua originaleEnglish
pagine (da-a)26-31
Numero di pagine6
RivistaUrologia Internationalis
Volume79
Stato di pubblicazionePublished - 2007

All Science Journal Classification (ASJC) codes

  • Urology

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