Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen

Claudia Pellerito; Girolamo Casella; Cristina Prinzivalli; Michelangelo Scopelliti; Salvatore Cataldo; Tiziana Fiore; Lorenzo Pellerito; Michele Abbate

Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen

Claudia Pellerito, Girolamo Casella, Cristina Prinzivalli, Michelangelo Scopelliti, Salvatore Cataldo, Tiziana Fiore, Lorenzo Pellerito, Michele Abbate

Risultato della ricerca: Article › peer review

Abstract

Several new diorganotin(IV) and triorganotin(IV) complexes with 4-amino-3- (4-chloro phenyl)]-butanoic acid ( = Baclofen) have been synthesized and their structure investigated both in the solid state and in solution phase through spectroscopic methods (FT-IR, Mössbauer, 1H and 13C NMR). According to experimental analytical data, the stoichiometry of the complexes has been proposed as R2SnBac2 and R3SnBac, respectively for diorganotin(IV) and triorganotin(IV) baclofen complexes. (Baclofen = HBac; R = Me, Bu, Ph).

Lingua originale	English
pagine (da-a)	139-152
Numero di pagine	14
Rivista	ATTI DELLA ACCADEMIA DI SCIENZE, LETTERE E ARTI DI PALERMO, PARTE PRIMA: SCIENZE
Volume	SERIE QUINTA, VOL.XXIV (TOMO I: Scienze)
Stato di pubblicazione	Published - 2008

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title = "Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen",

abstract = "Several new diorganotin(IV) and triorganotin(IV) complexes with 4-amino-3- (4-chloro phenyl)]-butanoic acid ( = Baclofen) have been synthesized and their structure investigated both in the solid state and in solution phase through spectroscopic methods (FT-IR, M{\"o}ssbauer, 1H and 13C NMR). According to experimental analytical data, the stoichiometry of the complexes has been proposed as R2SnBac2 and R3SnBac, respectively for diorganotin(IV) and triorganotin(IV) baclofen complexes. (Baclofen = HBac; R = Me, Bu, Ph).",

keywords = "Baclofen, FT-IR, Mossbauer, NMR, Organotin(IV), Baclofen, FT-IR, Mossbauer, NMR, Organotin(IV)",

author = "Claudia Pellerito and Girolamo Casella and Cristina Prinzivalli and Michelangelo Scopelliti and Salvatore Cataldo and Tiziana Fiore and Lorenzo Pellerito and Michele Abbate",

year = "2008",

language = "English",

volume = "SERIE QUINTA, VOL.XXIV (TOMO I: Scienze)",

pages = "139--152",

journal = "ATTI DELLA ACCADEMIA DI SCIENZE, LETTERE E ARTI DI PALERMO, PARTE PRIMA: SCIENZE",

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TY - JOUR

T1 - Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen

AU - Pellerito, Claudia

AU - Casella, Girolamo

AU - Prinzivalli, Cristina

AU - Scopelliti, Michelangelo

AU - Cataldo, Salvatore

AU - Fiore, Tiziana

AU - Pellerito, Lorenzo

AU - Abbate, Michele

PY - 2008

Y1 - 2008

N2 - Several new diorganotin(IV) and triorganotin(IV) complexes with 4-amino-3- (4-chloro phenyl)]-butanoic acid ( = Baclofen) have been synthesized and their structure investigated both in the solid state and in solution phase through spectroscopic methods (FT-IR, Mössbauer, 1H and 13C NMR). According to experimental analytical data, the stoichiometry of the complexes has been proposed as R2SnBac2 and R3SnBac, respectively for diorganotin(IV) and triorganotin(IV) baclofen complexes. (Baclofen = HBac; R = Me, Bu, Ph).

AB - Several new diorganotin(IV) and triorganotin(IV) complexes with 4-amino-3- (4-chloro phenyl)]-butanoic acid ( = Baclofen) have been synthesized and their structure investigated both in the solid state and in solution phase through spectroscopic methods (FT-IR, Mössbauer, 1H and 13C NMR). According to experimental analytical data, the stoichiometry of the complexes has been proposed as R2SnBac2 and R3SnBac, respectively for diorganotin(IV) and triorganotin(IV) baclofen complexes. (Baclofen = HBac; R = Me, Bu, Ph).

KW - Baclofen

KW - FT-IR

KW - Mossbauer

KW - NMR

KW - Organotin(IV)

KW - Baclofen

KW - FT-IR

KW - Mossbauer

KW - NMR

KW - Organotin(IV)

UR - http://hdl.handle.net/10447/35104

M3 - Article

SN - 0365-0448

VL - SERIE QUINTA, VOL.XXIV (TOMO I: Scienze)

SP - 139

EP - 152

JO - ATTI DELLA ACCADEMIA DI SCIENZE, LETTERE E ARTI DI PALERMO, PARTE PRIMA: SCIENZE

JF - ATTI DELLA ACCADEMIA DI SCIENZE, LETTERE E ARTI DI PALERMO, PARTE PRIMA: SCIENZE

ER -

Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen

Abstract

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