Oil-in-Water fL Droplets by Interfacial Spontaneous Fragmentation and Their Electrical Characterization

Giuseppe Domenico Arrabito, Vittorio Ferrara, Bruno Giuseppe Pignataro, Vito Errico, Federica Caselli, Adele De Ninno, Vittorio Ferrara, Felicia Cavaleri

Risultato della ricerca: Articlepeer review

7 Citazioni (Scopus)


Inkjet printing is here employed for the first time as a method to produce femtoliter-scale oil droplets dispersed in water. In particular, picoliter-scale fluorinated oil (FC40) droplets are printed in the presence of perfluoro-1-octanol surfactant at a velocity higher than 5 m/s. Femtoliter-scale oil droplets in water are spontaneously formed through a fragmentation process at the water/air interface using minute amounts of nonionic surfactant (down to 0.003% v/v of Tween 80). This fragmentation occurs by a Plateau-Rayleigh mechanism at a moderately high Weber number (10(1)). A microfluidic chip with integrated microelectrodes allows droplets characterization in terms of number and diameter distribution (peaked at about 3 mu m) by means of electrical impedance measurements. These results show an unprecedented possibility to scale oil droplets down to the femtoliter scale, which opens up several perspectives for a tailored oil-in-water emulsion preparations, and cellular biology. fabrication for drug encapsulation, pharmaceutic preparations, and cellular biology.
Lingua originaleEnglish
pagine (da-a)4936-4945
Numero di pagine10
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.3100.3104???
  • ???subjectarea.asjc.3100.3110???
  • ???subjectarea.asjc.1600.1607???
  • ???subjectarea.asjc.1600.1603???


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