Nutritional and global indexes of progression in dementia: A 12-month prospective study

Nicola Veronese, Enzo Manzato, Agostino Girardi, Serena Granziera, Francesco Bolzetta, Nicola Veronese, Marina De Rui, Alessandra Coin, Giuseppe Sergi

Risultato della ricerca: Articlepeer review

5 Citazioni (Scopus)

Abstract

Background: To assess the influence of body mass index (BMI) on the progression of dementia. Methods: Sixty elderly outpatients with dementia followed for 12 months. All patients underwent clinical, cognitive, functional, and nutritional assessment at the baseline and after 12 months. Patients were divided into 2 groups by baseline BMI (< or ≥25 kg/m2). Results: Participants with a baseline BMI ≥25 kg/m2 had significantly higher Mini-Mental State Examination (MMSE) scores (21±5.1 vs 15.9±5.5; P < .001), while clinical dementia rating (CDR) and multidimensional prognostic index (MPI) scores were similar in the 2 groups. After 12 months, the MMSE score decreased significantly in both groups compared to the baseline, while the CDR and MPI scores increased significantly for patients with a baseline BMI <25 kg/m2. Conclusion: A BMI cutoff of 25 kg/m2 could be useful for identifying frail patients with dementia who will experience a more rapid global impairment, which could be assessed adequately using multidimensional evaluation tools. © The Author(s) 2012.
Lingua originaleEnglish
pagine (da-a)504-508
Numero di pagine5
RivistaAmerican Journal of Alzheimer's Disease and other Dementias
Volume27
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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