Nuclear Magnetic Resonance investigation of PVA-GTA FRicke gel dosimeters exposed to clinical photon beams

Risultato della ricerca: Other

Abstract

Fricke Xylenol Gel (FXG) dosimetric system is based on the radiation induced oxidation of ferrous (Fe2+) to ferric (Fe3+) ions.The application of Fricke gels for ionizing radiation dosimetry is continuously increasing worldwide due to their many favorable properties. However, one of their shortcomings is that ferrous and ferric ions diffuse in the gel matrix. To maintain the spatial integrity of the dose distribution, Fricke gels must be undergoing measurement within a few hours of their irradiation, so that ferric ions remain close to their point of production. Thus, the spatial integrity of the dose distribution in the Fricke gel is maintained.The gel matrix also contributes to the oxidation of ferrous ions during irradiation, increasing the chemical yield of ferric ions in aqueous solution and increasing the sensitivity of the dosimeter.The oxidation of ferrous ions also causes a reduction of the longitudinal nuclear magnetic relaxation time T1 which can be measured by means of Nuclear Magnetic Resonance Relaxometry (NMR) and Magnetic Resonance Imaging (MRI).The results presented are related to an experimental investigation conducted on Fricke Gels characterized by gelatinous matrix of Agarose or PVA.The dose calibration curves are reported and discussed from the point of view of the dosimeter use in clinical radiotherapy. This work has highlighted that the optimization of additives inside gel matrix is fundamental for optimizing photon sensitivity of these detectors. We can conclude that FXG dosimeters with optimal ferrous ammonium sulfate content can be regarded as a valuable dosimetric tool to achieve fast information on spatial dose distribution.
Lingua originaleEnglish
Numero di pagine1
Stato di pubblicazionePublished - 2016

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