Novel approaches for the treatment of hypertriglyceridemia

P, P.; Lopez Miranda, J.

Risultato della ricerca: Articlepeer review

8 Citazioni (Scopus)


increased risk for cardiovascular diseases (CVD). Increased triglycerides (TG) are a hallmark of atherogenic dyslipidemia, representing a marker of atherogenic small dense low-density lipoproteins (sdlDL). Importantly, non-fasting/ postprandial TG measurements tend to be emphasized in clinical practice for the prediction of CVD, and TG-lowering agents (primarily fibrates) have a beneficial effect on atherogenic dyslipidemia, reducing TG-rich particles and ultimately lowering the production of sdlDL. The combination of omega-3 fatty acids and statins is also recommended, and widely used in clinical practice for subjects with hypertriglyceridemia. However, a consensus on the optimal clinical use of these pharmacological agents is not fully established yet, and additional large clinical studies are needed. It seems that there is a favorable association between fish consumption and mortality from CVD, but it remains to be confirmed by future trials. Finally, there are a number of novel therapies, such as those targeting microsomal transport protein and its inhibitors, which represent new promising option for treating subjects with hypertriglyceridemia.
Lingua originaleEnglish
pagine (da-a)1869-1873
Numero di pagine5
RivistaExpert Opinion on Pharmacotherapy
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.3000.3004???
  • ???subjectarea.asjc.2700.2736???


Entra nei temi di ricerca di 'Novel approaches for the treatment of hypertriglyceridemia'. Insieme formano una fingerprint unica.

Cita questo