TY - JOUR
T1 - NMR relaxometry measurements of Fricke gel dosimeters exposed to neutrons
AU - Tomarchio, Elio Angelo
AU - Marrale, Maurizio
AU - Brai, Maria
AU - Tranchina, Luigi
AU - Longo, Anna
AU - Gallo, Salvatore
AU - Gagliardo, Cesare
AU - Marrale, Maurizio
AU - Longo, Anna
AU - Brai, Maria
AU - Gallo, Salvatore
AU - D'Errico, Francesco
AU - D'Errico, Francesco
AU - Tomarchio, Elio
AU - D'Errico, Francesco
PY - 2014
Y1 - 2014
N2 - Fricke infused gel matrices offer several features making them suitable for dosimetric applications; among the set here are tissue equivalence, low cost and ease of preparation. Their nuclear magnetic resonance (NMR) relaxation properties can be used as a radiation detector for the dosimetry of beams used in cancer therapy. In recent years neutron capture therapy has been resumed for the treatment of various types of cancer and it requires three-dimensional mapping of the neutron fields. In this work, we investigated this particular application through NMR relaxometry and MR imaging of Fricke gels exposed to neutrons. We analyzed both the R1 and R2 relaxation rates, which relate to the longitudinal T1 and transversal T2 relaxation times. In particular, we found that the relaxation rate R2 does not depend on the neutron fluence, where as the relaxation rate R1 increases linearly with the fluence. The magnetic resonance imaging acquisitions showed that T1-weighted images allow the characterization of samples exposed to different neutron fluences.
AB - Fricke infused gel matrices offer several features making them suitable for dosimetric applications; among the set here are tissue equivalence, low cost and ease of preparation. Their nuclear magnetic resonance (NMR) relaxation properties can be used as a radiation detector for the dosimetry of beams used in cancer therapy. In recent years neutron capture therapy has been resumed for the treatment of various types of cancer and it requires three-dimensional mapping of the neutron fields. In this work, we investigated this particular application through NMR relaxometry and MR imaging of Fricke gels exposed to neutrons. We analyzed both the R1 and R2 relaxation rates, which relate to the longitudinal T1 and transversal T2 relaxation times. In particular, we found that the relaxation rate R2 does not depend on the neutron fluence, where as the relaxation rate R1 increases linearly with the fluence. The magnetic resonance imaging acquisitions showed that T1-weighted images allow the characterization of samples exposed to different neutron fluences.
UR - http://hdl.handle.net/10447/96301
UR - http://www.sciencedirect.com/science/article/pii/S0969806X14002242
M3 - Article
SN - 0969-806X
VL - 104
JO - Radiation Physics and Chemistry
JF - Radiation Physics and Chemistry
ER -