Neutron flux and gamma dose measurement in the BNCT irradiation facility at the TRIGA reactor of the University of Pavia

Salvatore Gallo, Maurizio Marrale, Antonio Bartolotta, Prata, Altieri, Bortolussi, Marrale, Protti, Farias, Postuma, Carante, Fatemi, Salvatore Gallo, Bartolotta, Ferrari, Giuseppina Iacoviello, Prata, Nigg, González, Ballarini

Risultato della ricerca: Articlepeer review

10 Citazioni (Scopus)

Abstract

University of Pavia is equipped with a TRIGA Mark II research nuclear reactor, operating at a maximum steadystate power of 250 kW. It has been used for many years to support Boron Neutron Capture Therapy (BNCT)research. An irradiation facility was constructed inside the thermal column of the reactor to produce a sufficientthermal neutron flux with low epithermal and fast neutron components, and low gamma dose. In this irradiationposition, the liver of two patients affected by hepatic metastases from colon carcinoma were irradiated afterborated drug administration. The facility is currently used for cell cultures and small animal irradiation.Measurements campaigns have been carried out, aimed at characterizing the neutron spectrum and thegamma dose component. The neutron spectrum has been measured by means of multifoil neutron activationspectrometry and a least squares unfolding algorithm; gamma dose was measured using alanine dosimeters.Results show that in a reference position the thermal neutron flux is (1.20 ± 0.03) × 1010 cm−2 s−1 when thereactor is working at the maximum power of 250 kW, with the epithermal and fast components, respectively, 2and 3 orders of magnitude lower than the thermal component. The ratio of the gamma dose with respect to thethermal neutron fluence is 1.2 × 10−13 Gy/(n/cm2).
Lingua originaleEnglish
pagine (da-a)113-120
Numero di pagine8
RivistaNUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION B, BEAM INTERACTIONS WITH MATERIALS AND ATOMS
Volume414
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.3100.3106???
  • ???subjectarea.asjc.3100.3105???

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