TY - JOUR
T1 - Native Mitral Valve Endocarditis Caused by Neisseria elongata subsp. nitroreducens in a Patient with Marfan Syndrome: First Case in Italy and Review of the Literature
AU - Giammanco, Anna
AU - Fasciana, Teresa Maria Assunta
AU - Midiri, Massimo
AU - Novo, Salvatore
AU - Grassedonio, Emanuele
AU - Novo, Giuseppina
AU - Triolo, Oreste Fabio
AU - Carita', Patrizia
AU - Parrinello, Rossella
AU - Argano, Vincenzo
PY - 2016
Y1 - 2016
N2 - Neisseria elongata (NE) is an aerobic Gram-negative organism that constitutes part of the commensal human normal oropharyngeal flora. Although previously considered not to be pathogenic, it has been recognized as an occasional cause of significant infections in humans. We report here the first case in Italy of infective endocarditis of a native prolapsing mitral valve in a patient with Marfan syndrome, caused by NE subspecies nitroreducens which has been rarely isolated from clinical specimens. The culprit organism has been confirmed by mass spectrometry directly from the positive blood culture, as previously reported. The amplified gene has been deposited in GenBank under accession number KT591873. In spite of the reported aggressive nature of NE, clinical remission was promptly obtained, there being no requirement for surgery.
AB - Neisseria elongata (NE) is an aerobic Gram-negative organism that constitutes part of the commensal human normal oropharyngeal flora. Although previously considered not to be pathogenic, it has been recognized as an occasional cause of significant infections in humans. We report here the first case in Italy of infective endocarditis of a native prolapsing mitral valve in a patient with Marfan syndrome, caused by NE subspecies nitroreducens which has been rarely isolated from clinical specimens. The culprit organism has been confirmed by mass spectrometry directly from the positive blood culture, as previously reported. The amplified gene has been deposited in GenBank under accession number KT591873. In spite of the reported aggressive nature of NE, clinical remission was promptly obtained, there being no requirement for surgery.
UR - http://hdl.handle.net/10447/205212
M3 - Article
JO - CASE REPORT IN INFECTIOUS DISEASES
JF - CASE REPORT IN INFECTIOUS DISEASES
SN - 2090-6625
ER -