Mortality rates and risk factors for emergent open repair of abdominal aortic aneurysms in the endovascular era

Felice Pecoraro, Steffen Gloekler, Felice Pecoraro, Caecilia E. Mader, Lyubov Chaykovska, Frank J. Veith, Mario Lachat, Frank J. Veith, Thomas Neff, Thomas Neff, Mario Lachat, Nicola Mangialardi, Neal S. Cayne, Malgorzata Roos

Risultato della ricerca: Article

5 Citazioni (Scopus)

Abstract

The background of this paper is to report the mortality at 30 and 90 days and at mean follow-up after open abdominal aortic aneurysms (AAA) emergent repair and to identify predictive risk factors for 30- and 90-day mortality. Between 1997 and 2002, 104 patients underwent emergent AAA open surgery. Symptomatic and ruptured AAAs were observed, respectively, in 21 and 79% of cases. Mean patient age was 70 (SD 9.2) years. Mean aneurysm maximal diameter was 7.4 (SD 1.6) cm. Primary endpoints were 30- and 90-day mortality. Significant mortality-related risk factor identification was the secondary endpoint. Open repair trend and its related perioperative mortality with a per-year analysis and a correlation subanalysis to identify predictive mortality factor were performed. Mean follow-up time was 23 (SD 23) months. Overall, 30-day mortality was 30%. Significant mortality-related risk factors were the use of computed tomography (CT) as a preoperative diagnostic tool, AAA rupture, preoperative shock, intraoperative cardiopulmonary resuscitation (CPR), use of aortic balloon occlusion, intraoperative massive blood transfusion (MBT), and development of abdominal compartment syndrome (ACS). Previous abdominal surgery was identified as a protective risk factor. The mortality rate at 90 days was 44%. Significant mortality-related risk factors were AAA rupture, aortocaval fistula, peripheral artery disease (PAD), preoperative shock, CPR, MBT, and ACS. The mortality rate at follow-up was 45%. Correlation analysis showed that MBT, shock, and ACS are the most relevant predictive mortality factor at 30 and 90 days. During the transition period from open to endovascular repair, open repair mortality outcomes remained comparable with other contemporary data despite a selection bias for higher risk patients. MBT, shock, and ACS are the most pronounced predictive mortality risk factors.
Lingua originaleEnglish
pagine (da-a)129-136
Numero di pagine8
RivistaUpdates in Surgery
Volume70
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Surgery

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    Pecoraro, F., Gloekler, S., Pecoraro, F., Mader, C. E., Chaykovska, L., Veith, F. J., Lachat, M., Veith, F. J., Neff, T., Neff, T., Lachat, M., Mangialardi, N., Cayne, N. S., & Roos, M. (2018). Mortality rates and risk factors for emergent open repair of abdominal aortic aneurysms in the endovascular era. Updates in Surgery, 70, 129-136.