Moral Cognition and Multiple Sclerosis: A Neuropsychological Study

Paolo Ragonese, Giuseppe Salemi, Nicola Canessa, Chiara Cerami, Alessandra Dodich

Risultato della ricerca: Article

4 Citazioni (Scopus)

Abstract

OBJECTIVES:Recent literature proved that social cognition impairments may characterize the neuropsychological profile of Multiple Sclerosis (MS) patients. However, little is still known about moral cognition in MS. In this study, we evaluated non-social, social, and moral cognitive performances in 45 relapsing-remitting MS patients.METHODS:Patients underwent the Brief International Cognitive Assessment for Multiple Sclerosis battery, the Cognitive Estimation and Stroop tasks, the Ekman-60 Faces test, the Reading the Mind in the Eye and Story-based Empathy task. Additionally, a task of moral dilemmas including both "instrumental" and "incidental" conditions was administered to patients. Forty-five age-, gender- and education-matched healthy control subjects (HC) were enrolled for comparisons.RESULTS:The majority of patients (i.e., 77.6%) showed deficits at non-social tasks, particularly in the executive domains. A subset of MS sample (i.e., 24%) presented with emotion recognition and socio-affective processing impairments. Overall, MS patients showed comparable levels of moral judgment with respect to HC. The rate of yes/no response in resolution of moral dilemmas and scores of attribution of emotional valence were comparable between groups. Nevertheless, lower moral permissibility and emotional arousal, particularly for the instrumental dilemmas, characterized the MS profile. Significant correlations between the attribution of emotional valence to moral actions and mentalizing scores emerged.CONCLUSIONS:Our findings expand current literature on MS supporting not only deficits in executive and socio-emotional domains but also low levels of permissibility of immoral actions and emotional detachment in the moral judgment process.
Lingua originaleEnglish
pagine (da-a)319-326
Numero di pagine8
RivistaArchives of Clinical Neuropsychology
Volume34
Stato di pubblicazionePublished - 2019

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Cognition
Multiple Sclerosis
Healthy Volunteers
Relapsing-Remitting Multiple Sclerosis
Theory of Mind
Arousal
Reading
Emotions
Education

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Psychiatry and Mental health

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Moral Cognition and Multiple Sclerosis: A Neuropsychological Study. / Ragonese, Paolo; Salemi, Giuseppe; Canessa, Nicola; Cerami, Chiara; Dodich, Alessandra.

In: Archives of Clinical Neuropsychology, Vol. 34, 2019, pag. 319-326.

Risultato della ricerca: Article

Ragonese, Paolo ; Salemi, Giuseppe ; Canessa, Nicola ; Cerami, Chiara ; Dodich, Alessandra. / Moral Cognition and Multiple Sclerosis: A Neuropsychological Study. In: Archives of Clinical Neuropsychology. 2019 ; Vol. 34. pagg. 319-326.
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abstract = "OBJECTIVES:Recent literature proved that social cognition impairments may characterize the neuropsychological profile of Multiple Sclerosis (MS) patients. However, little is still known about moral cognition in MS. In this study, we evaluated non-social, social, and moral cognitive performances in 45 relapsing-remitting MS patients.METHODS:Patients underwent the Brief International Cognitive Assessment for Multiple Sclerosis battery, the Cognitive Estimation and Stroop tasks, the Ekman-60 Faces test, the Reading the Mind in the Eye and Story-based Empathy task. Additionally, a task of moral dilemmas including both {"}instrumental{"} and {"}incidental{"} conditions was administered to patients. Forty-five age-, gender- and education-matched healthy control subjects (HC) were enrolled for comparisons.RESULTS:The majority of patients (i.e., 77.6{\%}) showed deficits at non-social tasks, particularly in the executive domains. A subset of MS sample (i.e., 24{\%}) presented with emotion recognition and socio-affective processing impairments. Overall, MS patients showed comparable levels of moral judgment with respect to HC. The rate of yes/no response in resolution of moral dilemmas and scores of attribution of emotional valence were comparable between groups. Nevertheless, lower moral permissibility and emotional arousal, particularly for the instrumental dilemmas, characterized the MS profile. Significant correlations between the attribution of emotional valence to moral actions and mentalizing scores emerged.CONCLUSIONS:Our findings expand current literature on MS supporting not only deficits in executive and socio-emotional domains but also low levels of permissibility of immoral actions and emotional detachment in the moral judgment process.",
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T1 - Moral Cognition and Multiple Sclerosis: A Neuropsychological Study

AU - Ragonese, Paolo

AU - Salemi, Giuseppe

AU - Canessa, Nicola

AU - Cerami, Chiara

AU - Dodich, Alessandra

PY - 2019

Y1 - 2019

N2 - OBJECTIVES:Recent literature proved that social cognition impairments may characterize the neuropsychological profile of Multiple Sclerosis (MS) patients. However, little is still known about moral cognition in MS. In this study, we evaluated non-social, social, and moral cognitive performances in 45 relapsing-remitting MS patients.METHODS:Patients underwent the Brief International Cognitive Assessment for Multiple Sclerosis battery, the Cognitive Estimation and Stroop tasks, the Ekman-60 Faces test, the Reading the Mind in the Eye and Story-based Empathy task. Additionally, a task of moral dilemmas including both "instrumental" and "incidental" conditions was administered to patients. Forty-five age-, gender- and education-matched healthy control subjects (HC) were enrolled for comparisons.RESULTS:The majority of patients (i.e., 77.6%) showed deficits at non-social tasks, particularly in the executive domains. A subset of MS sample (i.e., 24%) presented with emotion recognition and socio-affective processing impairments. Overall, MS patients showed comparable levels of moral judgment with respect to HC. The rate of yes/no response in resolution of moral dilemmas and scores of attribution of emotional valence were comparable between groups. Nevertheless, lower moral permissibility and emotional arousal, particularly for the instrumental dilemmas, characterized the MS profile. Significant correlations between the attribution of emotional valence to moral actions and mentalizing scores emerged.CONCLUSIONS:Our findings expand current literature on MS supporting not only deficits in executive and socio-emotional domains but also low levels of permissibility of immoral actions and emotional detachment in the moral judgment process.

AB - OBJECTIVES:Recent literature proved that social cognition impairments may characterize the neuropsychological profile of Multiple Sclerosis (MS) patients. However, little is still known about moral cognition in MS. In this study, we evaluated non-social, social, and moral cognitive performances in 45 relapsing-remitting MS patients.METHODS:Patients underwent the Brief International Cognitive Assessment for Multiple Sclerosis battery, the Cognitive Estimation and Stroop tasks, the Ekman-60 Faces test, the Reading the Mind in the Eye and Story-based Empathy task. Additionally, a task of moral dilemmas including both "instrumental" and "incidental" conditions was administered to patients. Forty-five age-, gender- and education-matched healthy control subjects (HC) were enrolled for comparisons.RESULTS:The majority of patients (i.e., 77.6%) showed deficits at non-social tasks, particularly in the executive domains. A subset of MS sample (i.e., 24%) presented with emotion recognition and socio-affective processing impairments. Overall, MS patients showed comparable levels of moral judgment with respect to HC. The rate of yes/no response in resolution of moral dilemmas and scores of attribution of emotional valence were comparable between groups. Nevertheless, lower moral permissibility and emotional arousal, particularly for the instrumental dilemmas, characterized the MS profile. Significant correlations between the attribution of emotional valence to moral actions and mentalizing scores emerged.CONCLUSIONS:Our findings expand current literature on MS supporting not only deficits in executive and socio-emotional domains but also low levels of permissibility of immoral actions and emotional detachment in the moral judgment process.

KW - Emotions/emotional processing

KW - Moral cognition

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KW - Multiple sclerosis

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JO - Archives of Clinical Neuropsychology

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