Modificazioni morfo-strutturali placentari nel ritardo di crescita asimmetrico idiopatico [Morphological and structural placental changes in intrauterine growth-restricted fetuses]

Orlando, E.; Barreca, P.; Guarnuto, G.; Lucido, A.

Risultato della ricerca: Article

Abstract

Objective: to evaluate the structural and developmental abnormalities of villous tissue coming from placentas of fetuses with IUGR. Patients and methods: placental examination of 45 patients with idiopathic IUGR was carried out in accordance with the guidelines of the "Gruppo Italiano di Anatomia Patologica". The diagnosis of IUGR was made on the basis of fetal growth restriction, amniotic fluid reduction and placental US imaging. Results: the placental microscopic examination showed villous alterations tipical of chronic placental ipoperfusion: ischemic villitis, accelerated villous maturity and placental infarctions. There was evidence of enhanced villous capillarization maybe due to a relative hypoxia of maternal intervillous circulating blood in ten placentas. Conclusion: asymmetric idiopathic IUGR seems to be correlated with alterations of angiogenesis in the initial pregnancy steps with resulting chronic placental ipoperfusion in late pregnancy.
Lingua originaleItalian
pagine (da-a)307-311
Numero di pagine5
RivistaGiornale Italiano di Ostetricia e Ginecologia
Volume30
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Cita questo

@article{7801b0f9728747829f87f0e65b7dcd11,
title = "Modificazioni morfo-strutturali placentari nel ritardo di crescita asimmetrico idiopatico [Morphological and structural placental changes in intrauterine growth-restricted fetuses]",
abstract = "Objective: to evaluate the structural and developmental abnormalities of villous tissue coming from placentas of fetuses with IUGR. Patients and methods: placental examination of 45 patients with idiopathic IUGR was carried out in accordance with the guidelines of the {"}Gruppo Italiano di Anatomia Patologica{"}. The diagnosis of IUGR was made on the basis of fetal growth restriction, amniotic fluid reduction and placental US imaging. Results: the placental microscopic examination showed villous alterations tipical of chronic placental ipoperfusion: ischemic villitis, accelerated villous maturity and placental infarctions. There was evidence of enhanced villous capillarization maybe due to a relative hypoxia of maternal intervillous circulating blood in ten placentas. Conclusion: asymmetric idiopathic IUGR seems to be correlated with alterations of angiogenesis in the initial pregnancy steps with resulting chronic placental ipoperfusion in late pregnancy.",
author = "{Orlando, E.; Barreca, P.; Guarnuto, G.; Lucido, A.} and {Lo Dico}, Giuseppe and Emiliano Maresi",
year = "2008",
language = "Italian",
volume = "30",
pages = "307--311",
journal = "Giornale Italiano di Ostetricia e Ginecologia",
issn = "0391-9013",
publisher = "CIC Edizioni Internazionali s.r.l.",

}

TY - JOUR

T1 - Modificazioni morfo-strutturali placentari nel ritardo di crescita asimmetrico idiopatico [Morphological and structural placental changes in intrauterine growth-restricted fetuses]

AU - Orlando, E.; Barreca, P.; Guarnuto, G.; Lucido, A.

AU - Lo Dico, Giuseppe

AU - Maresi, Emiliano

PY - 2008

Y1 - 2008

N2 - Objective: to evaluate the structural and developmental abnormalities of villous tissue coming from placentas of fetuses with IUGR. Patients and methods: placental examination of 45 patients with idiopathic IUGR was carried out in accordance with the guidelines of the "Gruppo Italiano di Anatomia Patologica". The diagnosis of IUGR was made on the basis of fetal growth restriction, amniotic fluid reduction and placental US imaging. Results: the placental microscopic examination showed villous alterations tipical of chronic placental ipoperfusion: ischemic villitis, accelerated villous maturity and placental infarctions. There was evidence of enhanced villous capillarization maybe due to a relative hypoxia of maternal intervillous circulating blood in ten placentas. Conclusion: asymmetric idiopathic IUGR seems to be correlated with alterations of angiogenesis in the initial pregnancy steps with resulting chronic placental ipoperfusion in late pregnancy.

AB - Objective: to evaluate the structural and developmental abnormalities of villous tissue coming from placentas of fetuses with IUGR. Patients and methods: placental examination of 45 patients with idiopathic IUGR was carried out in accordance with the guidelines of the "Gruppo Italiano di Anatomia Patologica". The diagnosis of IUGR was made on the basis of fetal growth restriction, amniotic fluid reduction and placental US imaging. Results: the placental microscopic examination showed villous alterations tipical of chronic placental ipoperfusion: ischemic villitis, accelerated villous maturity and placental infarctions. There was evidence of enhanced villous capillarization maybe due to a relative hypoxia of maternal intervillous circulating blood in ten placentas. Conclusion: asymmetric idiopathic IUGR seems to be correlated with alterations of angiogenesis in the initial pregnancy steps with resulting chronic placental ipoperfusion in late pregnancy.

UR - http://hdl.handle.net/10447/39437

M3 - Article

VL - 30

SP - 307

EP - 311

JO - Giornale Italiano di Ostetricia e Ginecologia

JF - Giornale Italiano di Ostetricia e Ginecologia

SN - 0391-9013

ER -