Modificazioni di alcuni parametri immunitari in un gruppo di sportivi amatoriali praticanti maratona ed ultramaratona

M., T.

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1 Citazione (Scopus)

Abstract

The function of the Immune System is that to distinguish "self" from "not-self". The immune answer includes a "specific" phase and a "not specific" phase. The phagocytes, as macrophages, granulocytes and natural killer cells constitute a successful defense against viral infections and some types of cancer. The Specific System is made by Ly-T and Ly-B: the first are divided into Ly-T helper and Ly-T suppressor; the second differentiates into Plasmacytes. The IgA, present into the nasal mucosa and the bronchial secretion, represent an early defense, able to block virus penetration. The data of the research show that a moderate exercise can limit the immune depression. It has been supposed that a moderate phisic and regular training can maintain "well-trained" the immune system by potentiating the immune. Ten amateur runners, 8 males and 2 females, who have been practicing a run of resistence, have been selected and they have been monitorated, through haematic sample and ergometric tests for a period of 8 months. The obtained values have been compared to those of the group of control. No significant modifications have been observed in the lymphocyte's underpopulations T-helper and T cytotoxic-suppressor and the relationship CD4/CD8 seemed the same to the control group. Every athlete shows, on the contrary, levels of NK cells, CD3-CD16+CD56+, superior as regard as the control group. The athlets have been reconsidered after 7 days and no particular modifications have been observed in the lymphocytes T helper and T cytotoxic-suppressor, while the levels of the NK, CD3-GD16+CD56+ cells, have showed a sensible reduction as regard the beginning levels. The obtained data showed in every athlets a medium percentage of NK cells superior as regard to the control group; the same value is strictly related to the clinic date, which shows to the anamnesis the absence of the flu syndromes in the last 7 years. The actual hypothesis is about the relationship between the nervous system and the immune system and is confirmed by the presence on the NK cells of an high concentration of the β-adrenergic, principally of the subtype β-2. There is a relationship between the aerobic regular training and increasing of NK that is stable during the time because phisic-training can develop a stable increasing of this lymphocytes's underpopulation, producing some lasting benefic effects the immune system.
Lingua originaleItalian
pagine (da-a)203-206
Numero di pagine4
RivistaMedicina dello Sport
Volume58
Stato di pubblicazionePublished - 2005

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cita questo

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title = "Modificazioni di alcuni parametri immunitari in un gruppo di sportivi amatoriali praticanti maratona ed ultramaratona",
abstract = "The function of the Immune System is that to distinguish {"}self{"} from {"}not-self{"}. The immune answer includes a {"}specific{"} phase and a {"}not specific{"} phase. The phagocytes, as macrophages, granulocytes and natural killer cells constitute a successful defense against viral infections and some types of cancer. The Specific System is made by Ly-T and Ly-B: the first are divided into Ly-T helper and Ly-T suppressor; the second differentiates into Plasmacytes. The IgA, present into the nasal mucosa and the bronchial secretion, represent an early defense, able to block virus penetration. The data of the research show that a moderate exercise can limit the immune depression. It has been supposed that a moderate phisic and regular training can maintain {"}well-trained{"} the immune system by potentiating the immune. Ten amateur runners, 8 males and 2 females, who have been practicing a run of resistence, have been selected and they have been monitorated, through haematic sample and ergometric tests for a period of 8 months. The obtained values have been compared to those of the group of control. No significant modifications have been observed in the lymphocyte's underpopulations T-helper and T cytotoxic-suppressor and the relationship CD4/CD8 seemed the same to the control group. Every athlete shows, on the contrary, levels of NK cells, CD3-CD16+CD56+, superior as regard as the control group. The athlets have been reconsidered after 7 days and no particular modifications have been observed in the lymphocytes T helper and T cytotoxic-suppressor, while the levels of the NK, CD3-GD16+CD56+ cells, have showed a sensible reduction as regard the beginning levels. The obtained data showed in every athlets a medium percentage of NK cells superior as regard to the control group; the same value is strictly related to the clinic date, which shows to the anamnesis the absence of the flu syndromes in the last 7 years. The actual hypothesis is about the relationship between the nervous system and the immune system and is confirmed by the presence on the NK cells of an high concentration of the β-adrenergic, principally of the subtype β-2. There is a relationship between the aerobic regular training and increasing of NK that is stable during the time because phisic-training can develop a stable increasing of this lymphocytes's underpopulation, producing some lasting benefic effects the immune system.",
keywords = "CD16 antigen, immunoglobulin A, CD3 antigen",
author = "{M., T.} and Salvatore Amato and Giuseppe Francavilla and Serena Tripoli",
year = "2005",
language = "Italian",
volume = "58",
pages = "203--206",
journal = "Medicina dello Sport",
issn = "0025-7826",
publisher = "Edizioni Minerva Medica S.p.A.",

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TY - JOUR

T1 - Modificazioni di alcuni parametri immunitari in un gruppo di sportivi amatoriali praticanti maratona ed ultramaratona

AU - M., T.

AU - Amato, Salvatore

AU - Francavilla, Giuseppe

AU - Tripoli, Serena

PY - 2005

Y1 - 2005

N2 - The function of the Immune System is that to distinguish "self" from "not-self". The immune answer includes a "specific" phase and a "not specific" phase. The phagocytes, as macrophages, granulocytes and natural killer cells constitute a successful defense against viral infections and some types of cancer. The Specific System is made by Ly-T and Ly-B: the first are divided into Ly-T helper and Ly-T suppressor; the second differentiates into Plasmacytes. The IgA, present into the nasal mucosa and the bronchial secretion, represent an early defense, able to block virus penetration. The data of the research show that a moderate exercise can limit the immune depression. It has been supposed that a moderate phisic and regular training can maintain "well-trained" the immune system by potentiating the immune. Ten amateur runners, 8 males and 2 females, who have been practicing a run of resistence, have been selected and they have been monitorated, through haematic sample and ergometric tests for a period of 8 months. The obtained values have been compared to those of the group of control. No significant modifications have been observed in the lymphocyte's underpopulations T-helper and T cytotoxic-suppressor and the relationship CD4/CD8 seemed the same to the control group. Every athlete shows, on the contrary, levels of NK cells, CD3-CD16+CD56+, superior as regard as the control group. The athlets have been reconsidered after 7 days and no particular modifications have been observed in the lymphocytes T helper and T cytotoxic-suppressor, while the levels of the NK, CD3-GD16+CD56+ cells, have showed a sensible reduction as regard the beginning levels. The obtained data showed in every athlets a medium percentage of NK cells superior as regard to the control group; the same value is strictly related to the clinic date, which shows to the anamnesis the absence of the flu syndromes in the last 7 years. The actual hypothesis is about the relationship between the nervous system and the immune system and is confirmed by the presence on the NK cells of an high concentration of the β-adrenergic, principally of the subtype β-2. There is a relationship between the aerobic regular training and increasing of NK that is stable during the time because phisic-training can develop a stable increasing of this lymphocytes's underpopulation, producing some lasting benefic effects the immune system.

AB - The function of the Immune System is that to distinguish "self" from "not-self". The immune answer includes a "specific" phase and a "not specific" phase. The phagocytes, as macrophages, granulocytes and natural killer cells constitute a successful defense against viral infections and some types of cancer. The Specific System is made by Ly-T and Ly-B: the first are divided into Ly-T helper and Ly-T suppressor; the second differentiates into Plasmacytes. The IgA, present into the nasal mucosa and the bronchial secretion, represent an early defense, able to block virus penetration. The data of the research show that a moderate exercise can limit the immune depression. It has been supposed that a moderate phisic and regular training can maintain "well-trained" the immune system by potentiating the immune. Ten amateur runners, 8 males and 2 females, who have been practicing a run of resistence, have been selected and they have been monitorated, through haematic sample and ergometric tests for a period of 8 months. The obtained values have been compared to those of the group of control. No significant modifications have been observed in the lymphocyte's underpopulations T-helper and T cytotoxic-suppressor and the relationship CD4/CD8 seemed the same to the control group. Every athlete shows, on the contrary, levels of NK cells, CD3-CD16+CD56+, superior as regard as the control group. The athlets have been reconsidered after 7 days and no particular modifications have been observed in the lymphocytes T helper and T cytotoxic-suppressor, while the levels of the NK, CD3-GD16+CD56+ cells, have showed a sensible reduction as regard the beginning levels. The obtained data showed in every athlets a medium percentage of NK cells superior as regard to the control group; the same value is strictly related to the clinic date, which shows to the anamnesis the absence of the flu syndromes in the last 7 years. The actual hypothesis is about the relationship between the nervous system and the immune system and is confirmed by the presence on the NK cells of an high concentration of the β-adrenergic, principally of the subtype β-2. There is a relationship between the aerobic regular training and increasing of NK that is stable during the time because phisic-training can develop a stable increasing of this lymphocytes's underpopulation, producing some lasting benefic effects the immune system.

KW - CD16 antigen, immunoglobulin A, CD3 antigen

UR - http://hdl.handle.net/10447/11451

M3 - Article

VL - 58

SP - 203

EP - 206

JO - Medicina dello Sport

JF - Medicina dello Sport

SN - 0025-7826

ER -