Microstructural Assessment of Rodent Behavior in the Hole-Board Experimental Assay

Risultato della ricerca: Otherpeer review


The aim of the present methodological article was to assess whether a microstructure of hole-exploratory activity can be demonstrated in rats tested in the hole-board, an experimental assay widely used to study anxiety-related behaviors in rodents. Six never properly described holeexploratorybehavioral components were identified: activedip,static-dip, rapid-dip, circular-sniff, point-sniff and central-sniff. Results, assessed by means of descriptive and multivariate approaches, reveal a complex microstructuralorganization of these behavioral elements. The hypothesis of an important role of the relationships between point-sniff and head dipping activities, in anxiety-related holeexploratory behavior, is proposed. It is suggested that the microstructural analysis can evidence even subtle behavioral changes induced by manipulations of animal anxiety condition.
Lingua originaleEnglish
Numero di pagine4
Stato di pubblicazionePublished - 2010


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