Metastatic Renal Cell Carcinoma to Submandibular Gland: A Rare Occurrence

Adriana Cordova, Nino Dispensa, Adriana Tuttolomondo, Carlo Melloni

Risultato della ricerca: Articlepeer review


Approximately 20-30% of patients affected by renal cell carcinoma (RCC) present with metastatic disease, and20% to 40% undergoing nephrectomy for clinically localized disease will develop metastases. A 53 years old femalepatient developed a left submandibular swelling. Four years before she experienced a left radical nephrectomy for aclear cell tumor and two years later right kidney was removed for a cancer having the same histologic subtype. Inthat circumstance duodenal pancreasectomy was required for infiltration of pancreatic gland. A sialoadenectomy hasbeen performed and pathology demonstrated an intraglandular neoplasm with characteristics of a clear renal cellcarcinoma. Although it is extremely rare, submandibular salivary gland may be a site of RCC metastasis. Diagnosisof metastatic disease for patients affected by submandibular swelling with a previous history of RCC should bealways considered.
Lingua originaleEnglish
Numero di pagine0
Stato di pubblicazionePublished - 2015


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