Metastatic Renal Cell Carcinoma to Submandibular Gland: A Rare Occurrence

Nino Dispensa, Adriana Cordova, Adriana Tuttolomondo, Carlo Melloni

Risultato della ricerca: Article

Abstract

Approximately 20-30% of patients affected by renal cell carcinoma (RCC) present with metastatic disease, and20% to 40% undergoing nephrectomy for clinically localized disease will develop metastases. A 53 years old femalepatient developed a left submandibular swelling. Four years before she experienced a left radical nephrectomy for aclear cell tumor and two years later right kidney was removed for a cancer having the same histologic subtype. Inthat circumstance duodenal pancreasectomy was required for infiltration of pancreatic gland. A sialoadenectomy hasbeen performed and pathology demonstrated an intraglandular neoplasm with characteristics of a clear renal cellcarcinoma. Although it is extremely rare, submandibular salivary gland may be a site of RCC metastasis. Diagnosisof metastatic disease for patients affected by submandibular swelling with a previous history of RCC should bealways considered.
Lingua originaleEnglish
Numero di pagine0
RivistaDefault journal
Volume4
Stato di pubblicazionePublished - 2015

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Submandibular Gland
Renal Cell Carcinoma
Nephrectomy
Neoplasm Metastasis
Kidney
Neoplasms
Salivary Glands
Pathology

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Metastatic Renal Cell Carcinoma to Submandibular Gland: A Rare Occurrence. / Dispensa, Nino; Cordova, Adriana; Tuttolomondo, Adriana; Melloni, Carlo.

In: Default journal, Vol. 4, 2015.

Risultato della ricerca: Article

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T1 - Metastatic Renal Cell Carcinoma to Submandibular Gland: A Rare Occurrence

AU - Dispensa, Nino

AU - Cordova, Adriana

AU - Tuttolomondo, Adriana

AU - Melloni, Carlo

PY - 2015

Y1 - 2015

N2 - Approximately 20-30% of patients affected by renal cell carcinoma (RCC) present with metastatic disease, and20% to 40% undergoing nephrectomy for clinically localized disease will develop metastases. A 53 years old femalepatient developed a left submandibular swelling. Four years before she experienced a left radical nephrectomy for aclear cell tumor and two years later right kidney was removed for a cancer having the same histologic subtype. Inthat circumstance duodenal pancreasectomy was required for infiltration of pancreatic gland. A sialoadenectomy hasbeen performed and pathology demonstrated an intraglandular neoplasm with characteristics of a clear renal cellcarcinoma. Although it is extremely rare, submandibular salivary gland may be a site of RCC metastasis. Diagnosisof metastatic disease for patients affected by submandibular swelling with a previous history of RCC should bealways considered.

AB - Approximately 20-30% of patients affected by renal cell carcinoma (RCC) present with metastatic disease, and20% to 40% undergoing nephrectomy for clinically localized disease will develop metastases. A 53 years old femalepatient developed a left submandibular swelling. Four years before she experienced a left radical nephrectomy for aclear cell tumor and two years later right kidney was removed for a cancer having the same histologic subtype. Inthat circumstance duodenal pancreasectomy was required for infiltration of pancreatic gland. A sialoadenectomy hasbeen performed and pathology demonstrated an intraglandular neoplasm with characteristics of a clear renal cellcarcinoma. Although it is extremely rare, submandibular salivary gland may be a site of RCC metastasis. Diagnosisof metastatic disease for patients affected by submandibular swelling with a previous history of RCC should bealways considered.

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