Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women

Enrico Carmina, Francesco Giallauria, Domenico Tafuri, Francesco Manguso, Francesco Orio, Marcello Orio, Carlo Vigorito, Annamaria Colao, Stefano Palomba, Gaetano Lombardi

Risultato della ricerca: Article

27 Citazioni (Scopus)

Abstract

Abstract OBJECTIVE: The aim of the present study was to determine if the favourable cardiopulmonary and metabolic benefits induced by exercise training (ET) programme are maintained after its cessation. PATIENTS: Thirty-two young overweight polycystic ovary syndrome (PCOS) women matched for age and body mass index (BMI) with other 32 PCOS patients was enrolled. The first group [PCOS-T (trained)] underwent 24-week ET programme, whereas the second [PCOS-DT (detrained)] underwent 12-week ET programme followed by 12-week detraining period. METHODS: At baseline, after 12- and 24-week follow-up, all PCOS women were studied for their hormonal (ovarian and adrenal androgens), metabolic (glucose and insulin) and lipid profile, and underwent cardiopulmonary exercise test. RESULTS: After the initial 12-week ET programme, both PCOS-T and PCOS-DT groups, without differences between groups, showed a similar significant (P < 0.05) improvement in BMI, fasting insulin, areas under curve insulin (AUC(INS)), glucose and insulin AUC (AUC(GLU/INS)), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and maximal oxygen consumption at cardiopulmonary exercise test (VO2max). At 24-week follow-up, PCOS-T group showed a significant (P < 0.05) improvement in BMI, fasting insulin, AUC(INS), AUC(GLU/INS), LDL-C, HDL-C and VO2max, in comparison to baseline and 12-week follow-up. At same follow-up visit, the all parameters resulted significantly (P < 0.05) worsened in PCOS-DT group in comparison to 12-week follow-up and PCOS-T group. In PCOS-DT group, no parameter assessed at 24-week follow-up was significantly different in comparison with baseline. CONCLUSION: In young PCOS women, 12-week detraining resulted in a complete loss of the favourable adaptations obtained after ET
Lingua originaleEnglish
pagine (da-a)976-981
Numero di pagine6
RivistaClinical Endocrinology
Volume68
Stato di pubblicazionePublished - 2008

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Polycystic Ovary Syndrome
Exercise
Education
Area Under Curve
Insulin
Body Mass Index
Exercise Test
LDL Cholesterol
HDL Cholesterol
Fasting
Glucose
Oxygen Consumption
Androgens

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cita questo

Carmina, E., Giallauria, F., Tafuri, D., Manguso, F., Orio, F., Orio, M., ... Lombardi, G. (2008). Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women. Clinical Endocrinology, 68, 976-981.

Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women. / Carmina, Enrico; Giallauria, Francesco; Tafuri, Domenico; Manguso, Francesco; Orio, Francesco; Orio, Marcello; Vigorito, Carlo; Colao, Annamaria; Palomba, Stefano; Lombardi, Gaetano.

In: Clinical Endocrinology, Vol. 68, 2008, pag. 976-981.

Risultato della ricerca: Article

Carmina, E, Giallauria, F, Tafuri, D, Manguso, F, Orio, F, Orio, M, Vigorito, C, Colao, A, Palomba, S & Lombardi, G 2008, 'Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women', Clinical Endocrinology, vol. 68, pagg. 976-981.
Carmina, Enrico ; Giallauria, Francesco ; Tafuri, Domenico ; Manguso, Francesco ; Orio, Francesco ; Orio, Marcello ; Vigorito, Carlo ; Colao, Annamaria ; Palomba, Stefano ; Lombardi, Gaetano. / Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women. In: Clinical Endocrinology. 2008 ; Vol. 68. pagg. 976-981.
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abstract = "Abstract OBJECTIVE: The aim of the present study was to determine if the favourable cardiopulmonary and metabolic benefits induced by exercise training (ET) programme are maintained after its cessation. PATIENTS: Thirty-two young overweight polycystic ovary syndrome (PCOS) women matched for age and body mass index (BMI) with other 32 PCOS patients was enrolled. The first group [PCOS-T (trained)] underwent 24-week ET programme, whereas the second [PCOS-DT (detrained)] underwent 12-week ET programme followed by 12-week detraining period. METHODS: At baseline, after 12- and 24-week follow-up, all PCOS women were studied for their hormonal (ovarian and adrenal androgens), metabolic (glucose and insulin) and lipid profile, and underwent cardiopulmonary exercise test. RESULTS: After the initial 12-week ET programme, both PCOS-T and PCOS-DT groups, without differences between groups, showed a similar significant (P < 0.05) improvement in BMI, fasting insulin, areas under curve insulin (AUC(INS)), glucose and insulin AUC (AUC(GLU/INS)), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and maximal oxygen consumption at cardiopulmonary exercise test (VO2max). At 24-week follow-up, PCOS-T group showed a significant (P < 0.05) improvement in BMI, fasting insulin, AUC(INS), AUC(GLU/INS), LDL-C, HDL-C and VO2max, in comparison to baseline and 12-week follow-up. At same follow-up visit, the all parameters resulted significantly (P < 0.05) worsened in PCOS-DT group in comparison to 12-week follow-up and PCOS-T group. In PCOS-DT group, no parameter assessed at 24-week follow-up was significantly different in comparison with baseline. CONCLUSION: In young PCOS women, 12-week detraining resulted in a complete loss of the favourable adaptations obtained after ET",
author = "Enrico Carmina and Francesco Giallauria and Domenico Tafuri and Francesco Manguso and Francesco Orio and Marcello Orio and Carlo Vigorito and Annamaria Colao and Stefano Palomba and Gaetano Lombardi",
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T1 - Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women

AU - Carmina, Enrico

AU - Giallauria, Francesco

AU - Tafuri, Domenico

AU - Manguso, Francesco

AU - Orio, Francesco

AU - Orio, Marcello

AU - Vigorito, Carlo

AU - Colao, Annamaria

AU - Palomba, Stefano

AU - Lombardi, Gaetano

PY - 2008

Y1 - 2008

N2 - Abstract OBJECTIVE: The aim of the present study was to determine if the favourable cardiopulmonary and metabolic benefits induced by exercise training (ET) programme are maintained after its cessation. PATIENTS: Thirty-two young overweight polycystic ovary syndrome (PCOS) women matched for age and body mass index (BMI) with other 32 PCOS patients was enrolled. The first group [PCOS-T (trained)] underwent 24-week ET programme, whereas the second [PCOS-DT (detrained)] underwent 12-week ET programme followed by 12-week detraining period. METHODS: At baseline, after 12- and 24-week follow-up, all PCOS women were studied for their hormonal (ovarian and adrenal androgens), metabolic (glucose and insulin) and lipid profile, and underwent cardiopulmonary exercise test. RESULTS: After the initial 12-week ET programme, both PCOS-T and PCOS-DT groups, without differences between groups, showed a similar significant (P < 0.05) improvement in BMI, fasting insulin, areas under curve insulin (AUC(INS)), glucose and insulin AUC (AUC(GLU/INS)), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and maximal oxygen consumption at cardiopulmonary exercise test (VO2max). At 24-week follow-up, PCOS-T group showed a significant (P < 0.05) improvement in BMI, fasting insulin, AUC(INS), AUC(GLU/INS), LDL-C, HDL-C and VO2max, in comparison to baseline and 12-week follow-up. At same follow-up visit, the all parameters resulted significantly (P < 0.05) worsened in PCOS-DT group in comparison to 12-week follow-up and PCOS-T group. In PCOS-DT group, no parameter assessed at 24-week follow-up was significantly different in comparison with baseline. CONCLUSION: In young PCOS women, 12-week detraining resulted in a complete loss of the favourable adaptations obtained after ET

AB - Abstract OBJECTIVE: The aim of the present study was to determine if the favourable cardiopulmonary and metabolic benefits induced by exercise training (ET) programme are maintained after its cessation. PATIENTS: Thirty-two young overweight polycystic ovary syndrome (PCOS) women matched for age and body mass index (BMI) with other 32 PCOS patients was enrolled. The first group [PCOS-T (trained)] underwent 24-week ET programme, whereas the second [PCOS-DT (detrained)] underwent 12-week ET programme followed by 12-week detraining period. METHODS: At baseline, after 12- and 24-week follow-up, all PCOS women were studied for their hormonal (ovarian and adrenal androgens), metabolic (glucose and insulin) and lipid profile, and underwent cardiopulmonary exercise test. RESULTS: After the initial 12-week ET programme, both PCOS-T and PCOS-DT groups, without differences between groups, showed a similar significant (P < 0.05) improvement in BMI, fasting insulin, areas under curve insulin (AUC(INS)), glucose and insulin AUC (AUC(GLU/INS)), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and maximal oxygen consumption at cardiopulmonary exercise test (VO2max). At 24-week follow-up, PCOS-T group showed a significant (P < 0.05) improvement in BMI, fasting insulin, AUC(INS), AUC(GLU/INS), LDL-C, HDL-C and VO2max, in comparison to baseline and 12-week follow-up. At same follow-up visit, the all parameters resulted significantly (P < 0.05) worsened in PCOS-DT group in comparison to 12-week follow-up and PCOS-T group. In PCOS-DT group, no parameter assessed at 24-week follow-up was significantly different in comparison with baseline. CONCLUSION: In young PCOS women, 12-week detraining resulted in a complete loss of the favourable adaptations obtained after ET

UR - http://hdl.handle.net/10447/73443

M3 - Article

VL - 68

SP - 976

EP - 981

JO - Clinical Endocrinology

JF - Clinical Endocrinology

SN - 0300-0664

ER -